COVID-19 infection is a new disease and our knowledge is limited; day in and day out more and more interesting yet diverse observations are reported by the different research groups from different corners of the world. So, there is an urgent requirement of the invention of some effective and...
1. Since COVID-19 is a respiratory disease, we also tested A549 (a human alveolar epithelial cell line) for the assay development. However, due to the low permissiveness of A549 for SARS-CoV-2-Nluc infection, we included A549-hACE2 cells to enhance viral infection in our assay (Fig. ...
COVID-19 is the disease caused by infection with the SARS-CoV-2 virus. Since it emerged at the end of 2019, this virus has caused a global pandemic. COVID-19 can be mild, or even without symptoms at all. But it can also cause severe disease, leading to respiratory problems, organ f...
In this review we discuss the drugs suggested as therapy for COVID infection, with a focus on chloroquine and hydroxychloroquine. The list of drugs used for COVID treatment includes a combination of lopinavir and ritonavir, remdesivir, favipiravir, alpha锕妌terferon, ribavirin, atazanavir, umifeno...
Antifebrile drugs and antibacterial drugs are always prescribed. Remember, for viral infection, the doctor prescribes antibiotics and bottles to the patient is ineffective treatment! 3.无效治疗的病人有轻有重,有轻度呼吸衰竭到重度呼吸衰竭。 如果不能给予有效的治疗,就得插管。 很多病人就犹豫了, 90 岁...
Everyone should try and prevent the spread of COVID-19, whether you are vaccinated or not. The best way to prevent infection is to avoid exposure to the virus.Wash your hands regularly and thoroughly with soap and water (lather for 20 seconds), OR use an alcohol based (at least 60%) ...
To the best of our knowledge there is no existing database for drug virus association. There are several recent studies such as8,9,10,11 that have used docking for finding a treatment for COVID-19 infection. Our work however contrasts with the docking approach. While docking is based on ...
ImportanceAntiretroviral therapy (ART) is the cornerstone of prevention and management of HIV infection. ObjectiveTo evaluate new data and treatments and incorporate this information into updated recommendations for initiating therapy, monitoring individuals starting therapy, changing regimens, and preventing HI...
In the limited studies that have been conducted on COVID-19, it seems that in some severe cases our immune response goes into overdrive without being able to clear the infection and this can increase the severity of the disease. When this happens, high levels of inflammation is found in th...
Mirabelli, C.et al. Morphological Cell Profiling of SARS-CoV-2 Infection Identifies Drug Repurposing Candidates for COVID-19.bioRxiv,https://doi.org/10.1101/2020.05.27.117184(2020). Cheng, H.et al. Inhibition of Ebola and Marburg Virus Entry by G Protein-Coupled Receptor Antagonists.J Virol89...