Inhalation has a stronger psychoactive effect than does ingestion. After inhalation, the concentration of THC in the brain is higher than that in the blood. Furthermore, after inhalation, THC and its metabolites quickly enter the bloodstream through the lungs, and the maximum concentration is reache...
When a vaccinated person smokes, the antibodies bind to any nicotine that enters the bloodstream。 The result is an extra—large molecule that is too big to enter the brain, thereby blocking most of the effects of the nicotine。 Clinical trials on people began in 2002。 So far, th...
In this model, the body acts like a single, uniform unit in which the drug can enter or leave the body easily (i.e., the model is “open” for the drug movement). For IV bolus administered drugs, the entire dose enters the bloodstream directly. This is followed by distribution of ...
Naked nucleic acids have poor in vivo stability and can degrade in the bloodstream. They undergo either enzymatic (nucleases and RNAse) or chemical (oxidation and hydrolysis) degradation in the blood and tissue fluids or are filtered and cleared by the kidneys.218Researchers have implemented several...
Other infection types can include ear and sinus infections, meningitis, bone and bloodstream infections. Drug-resistance to Streptococcus pneumoniae depends upon the area in which you live. When these bacteria are resistant to penicillin, they are often resistant to many other antibiotic classes. Resis...
When you put them into your body (often by swallowing, breathing in, or injecting them), drugs find their way into your bloodstream and are transported (运输) to parts of your body, such as your brain. In the brain, drugs may either strengthen or dull (使迟钝) your senses, change ...
Meningococcal disease (including infections of the lining of the brain and spinal cord [meningitis] and bloodstream [eg, bacteremia, septicemia)—Should not be used in patients with these conditions. Liver disease, chronic or Patients with poor nutrition status—Use with caution. May increase risk...
Naked nucleic acids have poor in vivo stability and can degrade in the bloodstream. They undergo either enzymatic (nucleases and RNAse) or chemical (oxidation and hydrolysis) degradation in the blood and tissue fluids or are filtered and cleared by the kidneys.218Researchers have implemented several...
A transdermal delivery gel consists of a vehicle, most commonly pluronic lecithin organogel (PLO gel), which delivers drugs via the transdermal route to the bloodstream. The micellar composition of PLO gel enhances skin penetration of the pharmaceutical agent present in the formulation. PLO gel...
In recent years, the occurrence of a wide variety of drug-resistant diseases has led to an increase in interest in alternate therapies. Peptide-based drugs as an alternate therapy hold researchers’ attention in various therapeutic fields such as neurology, dermatology, oncology, metabolic diseases,...