Therefore, in each D-period repeat of the microfibril, there is a part containing five molecules in cross-section, called the “overlap”, and a part containing only four molecules, called the “gap”.[24] The triple-helices are also arranged in a hexagonal or quasihexagonal array in ...
2. Ester local anesthetics ? Commonly used local anesthetics containing the ester functional group are benzocaine, cocaine, procaine, and tetracaine. a. procaine(Novocain) ? Procaine is the prototype drug of the local anesthetics. It has the lowest potency (except for Benzocaine). ? It is used...
SC1-9-alkoxythio- C1-9 alkyl esters, C1-9 alkyloxybenzyl esters and cyclic esters, in which the two ester-forming oxygen atoms are connected via an alkyl chain with 1 to 5 carbon atoms and the alkyl chain with C1-9 alkyl , C1-9 alkoxy, C1-9 acyl and C1-9 acyloxy groups may be ...
Ester local anesthetics Commonly used local anesthetics containing the ester functional group are benzocaine, cocaine, procaine, and tetracaine. 28DRUGSUSEDFORANESTHESIAMUSCLERELAXATION用于麻醉的药物肌肉松弛a. procaine(Novocain)Procaine is the prototype drug of the local anesthetics. It has the lowest ...
Artemether, with improved lipid solubility due to the addition of a methyl group, was formulated as an oil injection and approved in China in 1987. Artesunate, a succinic acid monoester derivative of dihydroartemisinin, notable for its enhanced water solubility and bioavailability, was also approved...
berghei of carboxylic ester and carbonate compounds of dihydroartemisinin. Additionally, Yu and co-workers synthesized C10-substituted benzoates of dihydroartemisinin. The biological results indicated that the halogen- and nitro-containing molecules were similar to artemisinin in activity14, 15, except ...
The second approach involves mRNA vaccines, which activate the body’s immune response to combat infectious diseases and tumors by directly translating mRNA-containing antigen proteins. Compared with traditional inactivated vaccines, mRNA vaccines have advantages such as cell-free production, high production...
Zonisamide is a benzisoxazole derivative containing a sulfonamide group, used to treat seizures and also as an adjunctive in Parkinson's disease therapy in a few countries. In addition to its antiepileptic properties, zonisamide has proved to be neuroprotective in different models of neuronal damage ...
There was no sign of cloudiness up to 100 °C for the emulsion containing 1 mol dm−3 NaCl and MgSO4. In contrast, the polyethylene glycol surfactant did not demonstrate that ability and exhibited coalescence and flocculation in the solution. The difference in zeta potential among OSA-inulin...
This invention relates to a compound of formula (I), their salts, the preparation thereof and drugs containing same. The compounds of formula (I) have interesting pharmacological properties. Said comp