用Quizlet學習並牢記包含Sedative hypnotic drugs、Historical background、Mechanism of action等詞語及更多內容的單詞卡。
PPIs require ___ of treatment before significant inhibition is seen at steady state, since not all pumps on parietal cells are activated simultaneously. 2-5 days PPIs are metabolized by CYP___ and CYP___. 2C19 3A4 Asians have a pharmacogenetic polymorphism of ___ which slows the metabolis...
-are indigestable and metabolized by bacteria in gut into hhydrogen and organic acids name 3 examples 1x day dose hyperosmotic laxative -sorbitol -lactulose -polyetholene glycol or miralax what type of laxative can cause diarrhea and electrolyte disturbances and are a heabit forming with chronic ...
Glucocorticoids are metabolized & eliminated primarily by the liver - therefore in patients with hepatic failure/impaired hepatic function, WATCH OUT.Mechanism of action:These produce lipocortin which inhibits Phospholipase A2 (and decreases subsequent AA -->eicosanoid synthesis)Act as transcription factor...
The nurse will discuss the importance of which diagnostic lab tests to determine how effectively the medication is being metabolized and excreted? kidney function, liver function A history of an allergy to which would be a contraindication to the use of anticholinergics? (Select all that apply.)...
K CB (phase 3), prevent potassium from leaving the cell leading to an increase in Phase 2 (inc Ca) & prolong AP Tocainide Methyl group next to amide provides steric hindrance to hydrolysis by Amidases & increase t1/2 to 8-12hrs Mexiletine NO AMIDE BOND -ether not easily metabolized du...
Contraindicated in pregnancy/lactation, hepatic disease, renal impaired/dialysis, lactase deficiency or with alcohol lomitapide ___ is metabolized by CYP3A4 so it interacts with ketoconazole, clarithromycin, simvastatin (inhibitors). Increased risk of myopathy and rhabdomyolysis w/ concurrent statin use G...
用Quizlet學習並牢記包含A 3-year-old child has swallowed the contents of 2 bottles of a nasal decongestant whose primary ingredient is a potent, selective α-adrenoceptor agonist drug. Which of the following is a sign of α-receptor activation that may oc