cardiovascular systemcell membranesleft atriumIntroductionDiseases of the Cardiovascular SystemSummarydoi:10.1002/9780470698891.ch7Margaret JohnsonRae MorganBlackwell Science LtdRankin GO (2008). Drugs affecting the cardiovascular system. In: Lemke TL, Williams DA, Roche VF and Zito SW (eds). Foye's ...
Interactions affecting metabolism, distribution or elimination are not very common, apart from interactions with grapefruit juice. Grapefruit juice contains potent inhibitors of the cytochrome P450 (CYP) 3A4 system and may markedly increase the bioavailability of drugs that undergo significant presystemic ...
Drugs Affecting the Cardiovascular System4.1. Ezetimibe (Zetia)4.2. Rosuvastatin (Crestor)4.3. Nebivolol (Bystolic)4.4. Pitavastatin (Livalo)4.5. Prasugrel (Effient)4.6. Ticagrelor (Brilique, Brilinta)5. Drugs for Infectious Diseases5.1. Voriconazole (Vfend)5.2. Emtricitabine (Emtriva)5.3. Tripanavir ...
Promising drugs for future heart failure treatment include agents that modulate the neurohormonal system, vasodilators, anti-inflammatory drugs, mitotropes, which improve deranged energy metabolism of the failing heart, and myotropes, which increase cardiac contractility by affecting cardiac sarcomere ...
Finally, lorcaserin, a selective 5HT2C receptor agonist, does not seem to exert significant direct effects on the cardiovascular system though at very high concentrations this drug may also interact with other serotonin receptor subtypes and exert unwanted cardiovascular effects. In conclusion, the ...
(LCA10)161,162. LCA10 is an eye disorder, affecting the patient’s retina, caused by a mutation in theCEP290gene leading to severe visual impairment. EDIT-101 is an AAV-mediated CRISPR-Cas9 system aiming the restoration of CEP290 protein production through subretinal injection in patients ...
For more than three decades, it has been known that manipulation of dopaminergic system could affect glucose homesotasis in experimental animals. The notion that glucose homeostasis in human might be influenced by dopaminergic drugs has attracted a great deal of attention in the past two decades. ...
theantibiotics, which act against bacteria and fungi; quinacrine and other synthetics that act against malaria and other parasitic infections; cardiovascular drugs, includingbeta-blockersandACE inhibitors;diuretics, which increase the rate of urine flow; whole blood, plasma, and blood derivatives;...
(LCA10)161,162. LCA10 is an eye disorder, affecting the patient’s retina, caused by a mutation in theCEP290gene leading to severe visual impairment. EDIT-101 is an AAV-mediated CRISPR-Cas9 system aiming the restoration of CEP290 protein production through subretinal injection in patients ...
Many drugs have a site of action within the inner ear. The list includes therapeutic, diagnostic and ototoxic agents. Therapeutic agents are most useful in