Cancer, a complex and multifactorial disease, presents a significant challenge to global health. Despite significant advances in surgical, radiotherapeutic and immunological approaches, which have improved cancer treatment outcomes, drug therapy continues to serve as a key therapeutic strategy. However, the...
Chemotherapy remains the only treatment for TNBC, but chemotherapy does not specifically targetcancer cellsand causes debilitating side effects. A new, targeted therapy is needed to treat TNBC without adverse effects. "TNBC is a very aggressive type of breast cancer with a short survival rate due ...
Introduction: Bladder cancer (BCa) is a disease that predominantly affects adult and elderly populations. As people live longer, it will become even more frequent and consequently represents a big health problem for health-care providers and is a challenging clinical dilemma. In the elderly, the ...
Chemotherapy is one of the major therapeutic options for cancer treatment. Chemotherapy is often associated with a low therapeutic window due to its poor specificity towards tumor cells/tissues. Antibody-drug conjugate (ADC) technology may provide a potentially new therapeutic solution for cancer treatme...
Cancer is a highly complex, adaptive system that has the ability to rapidly evolve newphenotypicand genotypic profiles to circumvent therapy. Drug resistance threatens the longevity of drugs and restricts treatment options for patients, with high prevalence in all areas of oncology and infectious diseas...
While immunotherapy—a form of treatment that uses the body's immune system to recognize, attack and kill tumor cells—has given hope to people across the globe, it fails in a significant proportion of cancer patients. However, a new study published in the Nature journalCell Death Discoveryon...
A technique developed by University of Texas at Dallas and UT Southwestern Medical Center researchers to deliver medication through the blood-brain barrier has shown promise in a preclinical study for treating glioblastoma, the most common human brain cancer. ...
Cancer Drug Resistance is a peer-reviewed journal led by Editor-in-Chief Godefridus J. (Frits) Peters, covering drug resistance research on breast cancer, lymphatic cancer, hematological malignancies, thyroid cancer, lung cancer, stomach cancer, esophage
Cancer Drug Resistance is a peer-reviewed journal led by Editor-in-Chief Godefridus J. (Frits) Peters, covering drug resistance research on breast cancer, lymphatic cancer, hematological malignancies, thyroid cancer, lung cancer, stomach cancer, esophage
Pancreatic cancer is the fourth leading cause of cancer-related deaths in the USA. The high mortality rate is partly due to lack of effective treatments. This review summarizes the pathobiology and current treatment options for pancreatic cancer. Moreover, the review discusses the opportunities of ...