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Authors and Affiliations Department of Pharmacy Practice, College of Pharmacy, University of Nebraska Medical Center, 986145 Nebraska Medical Center, Omaha, NE, 68198-6145, USA Kimberly K. Scarsi & Stephanie M. Nitz Center for Global Health, Northwestern University Feinberg School of Medicine, Chicag...
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The primary efficacy outcome was 12-month tuberculosis disease free survival, while the primary safety outcome was the proportion of grade 3 or higher adverse events during the treatment period. We conducted an analysis of demographic, clinical, microbiologic, radiographic, and pharmacokinetic data and...
In some ways, the trial was especially well-suited to a decentralized, home-run model: (i) the targeted alteration was ultra-rare but could be identified by an NGS assay used nationally; and (ii) the ALK inhibitor tested – alectinib – was already FDA-approved (for the treatment of ALK...
UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA; University of Michigan Comprehensive Cancer Center, Ann Arbor, MI; UNMC Eppley Cancer Center at The Nebraska Medical Center, Omaha, NE; The University of Texas M. D. Anderson Cancer Center, Houston, ...
2. Treatment of Drug-Induced Nephrotoxicity The management of acute drug-induced nephrotoxicity usually involves patient hospitalization. At this stage, the overall goal is to maintain renal perfusion to ensure that the kidneys have sufficient blood/oxygen supply and restore their normal functions in ti...
However, the treatment of multiple myeloma presents a variety of unique challenges due to the complex molecular pathophysiology, intra-clonal heterogeneity, and the incurable status of the disease at this time. While the majority of patients respond to initial treatment, most will relapse, and ...
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