FDA Reverses Course and Approves Promising Yet Risky Drug to Treat MSPatients facing limited options for treating their relapsingmultiple sclerosis are celebrating...Munz, Michele
Suicide by drug overdose is preventable. Intentional self-poisoning with drugs kills as many males as females. The considerable differences in patterns of self-poisoning found in the various European countries are relevant to national efforts to improve diagnostics of suicide and appropriate specific pre...
These results suggest that the use of AhR antagonists might be a viable approach to prevent and treat NASH. LXRs are known as sterol sensors that impact cholesterol and lipid homeostasis, as well as inflammation. The hepatic functions of LXRs are well documented and the pathophysiological role of...
Recombinant antibodies are an emerging class of therapeutics with substantial promise to treat central nervous system (CNS) diseases such as Alzheimer's, Parkinson's, stroke, and brain cancers. However, poor blood-brain barrier (BBB) per... KR Patel - 《Managed Care》 被引量: 10发表: 2015年...
providing more possibilities for the treatment of clinical nervous system disorders. The breakthroughs in drug delivery routes and delivery vehicle research in the drug delivery system field have improved the efficacy of drugs used to treat nervous system diseases. The emergence of NDDSs has shown new...
7000 rare diseases and more than 300 million people are affected worldwide2,3. Because of their low prevalence and complex pathology, they are often difficult to diagnose and treat. A paradigm shift and systematic approach to drug discovery is the key for treatment of rare and intractable ...
Riluzole, a treatment for amyotrophic lateral sclerosis (ALS), has been shown to be an effective pretreatment that sensitizes glioma to radiation therapy. It also has synergistic effects in combination with select other drugs when used to treat GBM. [62] Cannabidiol, another ALS treatment, ...
numerous sulfonamide compounds have been synthesized and used to treat bacterial infections, and many studies of drug-microbiota interactions have sprouted among them. Until 2010 when it was first proposed, the term ‘pharmacomicrobiomics’ was used to describe the effects of alterations in microbiota ...
Objective: The aim was to evaluate the efficacy of zotepine in the treatment of acute episodes of schizophrenia. Method: Patients with acute exacerbation... SJ Cooper,J Tweed,J Raniwalla,... - 《Acta Psychiatr Scand》 被引量: 51发表: 2010年 Alcohol consumption after laryngectomy The aim ...
Moreover, novel vector protein formats as well as warheads targeting the tumour microenvironment are expected to improve the intratumour distribution or activation of ADCs, and consequently their anticancer activity for difficult-to-treat tumour types. However, toxicity remains a key issue in the ...