Although not a primary objective, the study will also confirm if convulsions are self-limiting and potentially evaluate emergency drugs (e.g., diazepam, phenytoin, or propofol) to treat any drug-induced seizures. Toxicokinetic sample collections (including...
FDA Reverses Course and Approves Promising Yet Risky Drug to Treat MSPatients facing limited options for treating their relapsingmultiple sclerosis are celebrating...Munz, Michele
目前,有多种方法用于测定ADC的DAR值,常用的方法有紫外分光光度法(UV)、疏水作用色谱法(HIC)、液质联用法(LC-MS)、反相高效液相色谱法(RP)、亲水作用色谱法(HILIC)、组织蛋白酶B(Cathepsin B)酶切法等,本文将对DAR值分析的常用方法进行介绍。 01 紫外分光光度法(UV) 紫外分光光度法基于朗伯比尔定律对DAR值进...
Results from Chinese trials testing a combination of antiviral drugs used to treat HIV against the new coronavirus are due in weeks, bringing hope that experts can find an effective treatment. But the World Health Organization has likened the epidemic's threat to terrorism and WH...
M. Natural products as sources of new drugs over the nearly four decades from 01/1981 to 09/2019. J. Nat. Prod. 83, 770–803 (2020). Article CAS PubMed Google Scholar Galon, J. & Bruni, D. Approaches to treat immune hot, altered and cold tumours with combination immunotherapies. ...
& Lobo, M. Transdermal clonidine in difficult-to-treat hypertension patients attending a specialist BP clinic in the United Kingdom. J. Hypertens. 35, e279 (2017). Article Google Scholar Nordmann, J.-P. et al. Measurement of treatment compliance using a medical device for glaucoma patients...
providing more possibilities for the treatment of clinical nervous system disorders. The breakthroughs in drug delivery routes and delivery vehicle research in the drug delivery system field have improved the efficacy of drugs used to treat nervous system diseases. The emergence of NDDSs has shown new...
The majority of these new drugs were chemotherapeutic agents (18 out of 21) followed by agents used to treat infectious diseases (7 out of 8) and neurologic disorders (5 out of 9). Twelve of the novel drugs (nearly 20%) had hepatotoxicity warnings and/or precautions specifically listed in...
R Lo,PY Li,S Saati,RN Agrawal,MS Humayun,E Meng 摘要: An implantable manually-actuated drug delivery device, consisting of a refillable drug reservoir, flexible cannula, check valve, and suture tabs, was investigated as a new approach for delivering pharmaceuticals to treat chronic ocular ...
ABI indicates ankle-brachial index; FAS, full-analysis set; and mITT, modified intention to treat. aJudged by the investigator to be unsuitable for the study for any other reason. Figure 2. Kaplan-Meier Plot of Time to Complete Healing in the Full-Analysis Set Population View LargeDownload ...