The article presents a lesson for pharmacist in counseling pregnant patients on drug therapy during pregnancy as part of continuing education. It talks about the placental transport of drugs, the mechanism of drug effects on fetus including physical malformations, pharmacologic effects, alterations of ...
Medical therapy in pregnancy is an inescapable scenario faced by all doctors. The fact that a vulnerable fetus is involved makes the situation all the more challenging. Almost all drugs on the market were not designed with pregnancy in mind and because of the fear of costly litigation, ...
Indications for the treatment of the pregnant woman fall into three general categories: mother and infant require treatment, only the mother should be treated, or only the infant. Directing therapy towards the affected subject is an important aspect of good care, although it is not the only one...
• Radiation therapy (e.g., using high-energy X-rays, gamma rays, or other charged particles) works by inducing strand breaks in DNA, which is more likely to cause death in rapidly dividing cells. However, it is well-established that radiation...
Governmental safety categories do not inform on how either pregnancy or lactation may alter the patient's response to therapy compared with the non-pregnant state, nor do they indicate the impact of common medical diseases on a drug's efficacy. In the absence of information many women are ...
Cardiovascular Drugs and Therapy . 2007 (4)Myocardial Ischaemia-reperfusion Injury is Attenuated by Intact Glucagon Like Peptide-1 (GLP-1) in the In ... AK Bose,MM Mocanu,RD Carr,... - 《Cardiovascular Drugs & Therapy》 被引量: 401发表: 2007年 Omega-3 ethylester concentrate: a review ...
that a landmark article published in the New England Journal of Medicine linked in utero DES exposure to a rare type of vaginal tumor in women whose mothers had received the drug during their pregnancy. This finding led US and European regulators to recommended that DES no longer be prescribed...
This introduction describes the fundamentals necessary to interpret therapeutic and other exposures during pregnancy that may adversely affect mother, embryo and baby. Of note is the discussion of the science involved with Reproductive and Developmental Pharmacology/Toxicology and its use in developing risk...
that a landmark article published in the New England Journal of Medicine linked in utero DES exposure to a rare type of vaginal tumor in women whose mothers had received the drug during their pregnancy. This finding led US and European regulators to recommended that DES no longer be prescribed...
Drug consumption and drug compliance in pregnancy were analysed in our study. Structured questionnaire and data from mothers were used as principal sources for analysis. Consumption of drugs and compliance with therapy were evaluated in 331 pregnant women, 60% city and 40% rural population, of ...