Ivermectin is an over 30-year-oldwonder drugthat treats life- and sight-threatening parasitic infections. Its lasting influence on global health has been so profound that two of the key researchers in its discovery and development won theNobel Prize in 2015. I've been aninfectious disease pharma...
DSF. These mice were then placed in the EPM apparatus, and their activity was monitored. To their surprise, the team found that mice treated with DSF spent significantly more time in the open arms of the apparatus, which indicates that they were less anxious. The team also...
Kukje Pharm said Monday that it has signed an agreement with Eyegene to co-develop EG-Mirotin, the world's first treatment for non-proliferative diabetic retinopathy. According to Kukje, EG-Mirotin is a new-concept biological drug that treats diabetic retinopathy by relieving symptoms of recurren...
A definitive RP-II trial might be appropriate for approval of a drug that treats a sufficiently rare disease for which a conventional phase III trial might be difficult or impossible to conduct. An important challenge rests in determining what would define a “sufficiently robust” data set for...
One drug that recently produced positive results in a clinical trial was the steroid dexamethasone. The drug, which treats Covid-19 by a different mechanism than remdesivir, has been on the U.S. market for decades to treat other diseases. It hasn't been authorized in the U.S. to treat ...
Researchers around the globe use multiple approaches to identify an effective approved drug (drug repurposing) that treats viral infections. Most of the drug repurposing approaches target spike protein or main protease. Here we use transmembrane serine protease 2 (TMPRSS2) as a target that can ...
North Korea already treats drug crime as a direct challenge to policy implemented by the Workers’ Party of Korea and has been conducting mop-up operations against drug criminals. However, with these efforts yielding no decrease in drug crime, the country’s authorities appear to have distributed...
Disease:COVID-19 Sales estimate:$3 billion (2024) Approved:May 25 Company:Pfizer The scoop:While not the first drug to treat COVID-19—that designationwentto a repurposed Ebola med from Gilead—Pfizer did gain approval for the first COVID-specific treatment in Paxlovid, getting...
. Examples: COVID-19 -> causes -> pneumonia, remdesevir -> treats -> COVID-19, inflammation -> coexists with -> COVID-19. A KG has several advantages - it enables end-to-end learning, it can integrate data from multiple sources, and enables continuous integration of heterogeneous ...