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Pena I, Pilar Manzano M, Cantizani J, Kessler A, et al. New compound sets identified from high throughput phenotypic screening against three kinetoplastid parasites: an open resource. Sci Rep. 2015;5:8771. ArticleCASPubMedPubMed CentralGoogle Scholar Martinez-Mayorga K, Byler KG, Ramirez-Herna...
This grants makes it possible for drug rehabs in Fort Lauderdale, West Palm Beach and Miami to provide hepatitis C testing and treatment. This is great news for this underserved population. It is also great news for the addiction treatment centers because a majority of their clients are at ri...
The trillions of microbes that make up the gut microbiome are an important contributor to health and disease. With respect to xenobiotics, particularly ora
References 203–205 report some striking phenotypic differences between mouse strains based on genetic variation, illustrating why testing compounds in mice with a single genetic background can be misleading. CAS PubMed Google Scholar Gatti, D. M., Weber, S. N., Goodwin, N. C., Lammert, F...
Functional approaches that rapidly and directly assess the response of patient cancer tissue to drugs or small molecules offer a promising way to improve drug testing, and have the potential to identify the best therapy for individual patients. We developed a digitally manufactured microfluidic platform...
War on Drugs The uncanny parallels between alcohol Prohibition and the 'war on drugs'. A bustle in the cage-row: the making of Rat Park This is a lengthy blog post about the behind-the-scene 'making of'Rat Park. Includes historical photographs of the actual Rat Park experiment from the ...
Drug induced bile duct injury is a frequently observed clinical problem leading to a wide range of pathological features. During the past decades, several agents have been identified with various postulated mechanisms of bile duct damage, however, mostly
routine INR testing is unsuitable [134,135,136,137]. Suitable dose monitoring tests have been outlined in Table2. Briefly, the diluted thrombin time (dTT) and ecarin clotting time (ECT) assays are sensitive to the magnitude of dabigatran’s anticoagulant effect and have a linear response to ...