Acarbose is a bacterial-derived α-glucosidase inhibitor clinically used to treat patients with type 2 diabetes. As type 2 diabetes is on the rise worldwide, the market demand for acarbose has also increased. Despite its significant therapeutic importanc
Drug nanoaggregates are particles that can deleteriously cause false positive results during drug screening efforts, but alternatively, they may be used to improve pharmacokinetics when developed for drug delivery purposes. The structural features of mol
rotated 90° to the left and run in the second dimension using chloroform:acetic acid:methanol:water (40:25:3:6,v/v/v/v) as a solvent system44. TLC plates were dried and charred with 10% concentrated sulfuric acid in absolute ethanol and heated at 110 °C for lipids visualization. NI...
Under a Creative Commons license Open accessAbstract As a γ-aminobutyric acid A receptor (GABAAR) inhibitor, etomidate fulfills several characteristics of an ideal anesthetic agent, such as rapid onset with rapid clearance and high potency, along with cardiovascular stability. Unfortunately, etomidate ...
3.1. Thin layer chromatography (TLC) TLC is a technique used for fast screening of samples to identify herbal products and to differentiate between herbal species [13], [14], [15], [16]. One of the major advantages of TLC is its tractability to optimize operational parameters, such as the...
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apathy towards human life, corruption, nexus and quid pro quo between unscrupulous license holders, analytical laboratories elements in the industries department controlling the award of rate contracts, manufacturers, traders, merchants, suppliers, the Food and Drugs Administration and persons holding minist...
These plates were heated using heat gun for 1 min to visualize the separated compounds which were detected on the basis of their R f values visually and by the color of the spots generated [34]. The TLC plate used for bioautography was placed over LB agar containing 2 μl of overnight...
Tyrosinase-based TLC (thin layer chromatography) was developed for screening of anti-melanogenic drugs. In particular, this technique enables researchers to identify melanogenic inhibitor(s) in tested mixtures with the naked eye. In comparison with traditional colorimetric screening assays for tyrosinase...
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link ...