The side effects of nitrates include general effects common to most vasodilators and specific effects unique to nitrates. The general effects derive from the same properties which are responsible for the therapeutic effect of nitrates, mainly peripheral vasodilation. In addition, the alcoholic diluents ...
Whenever two or moredrugsare being taken, there is a chance that there will be an interaction between the drugs. The interaction may increase or decrease the effectiveness of the drugs or their side effects. The likelihood of drug interactions increases as the number of drugs being taken increas...
Lionel H. Opie.Calcium channel antagonists part IV: Side effects and contraindications drug interactions and combinations[J]. Cardiovascular Drugs and Therapy .1988(2)Lionel H. Opie. Calcium channel antagonists part IV: Side effects and contraindications drug interactions and combinations[J]. ...
recent developments infer interactions from neighbors (evolutionarily related proteins)27,28where such interactions are known. However, they have not yet been tested on a large scale, e.g. on DrugBank drugs8when there are no known interactions for a given drug or a target...
Design/methodology/approach – Examples from the literature covering compositions of food-drug, food-drug interactions, and dietary habits were collected from former works. Findings – Major side-effects of some diet(food) on drugs include alteration in absorption by fatty, high protein and fiber ...
Management of side effects In case of anaphylactic shock, immediate resuscitation should be performed, ensuring airway patency, providing oxygen, and administering adrenaline and corticosteroids. Drug interactions 1. Aminoglycosides: Combination with Ticarcillin disodium salt has a synergistic effect. ...
Drug-drug interaction (DDI) is an important topic for public health and thus attracts attention from both academia and industry. Here we hypothesize that clinical side effects (SEs) provide a human phenotypic profile and can be translated into the develo
They reported that cannabidol "may have modest efficacy and be appropriate for children with severe epilepsy, but attention must be paid to potential side effects and drug interactions". There is still no evidence to guide physicians in ranking cannabidiol among current antiepileptic drugs and it ...
This knowledge is already being used to strengthen drug safety information by helping to uncover real-world cases, improving our understanding of how drugs are being used, and shedding light on little-known side effects and drug interactions....
Drug drug interactions (DDIs) are crucial for drug research and pharmacologia. Recently, graph neural networks (GNNs) have handled these interactions successfully and shown great predictive performance, but most computational approaches are built on an unsigned graph that commonly represents assortative ...