both of these mechanisms [5]. Moreover, the target-protein modification that results in making the bacteria less susceptible to the drug can also aid in drug resistance. For example, theermgene methylates the adenine at position 2058 of the 50s rRNA resulting in drug resistant bacteria [6]. ...
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At each node, the resistance phenotype (resistant, susceptible or unknown) and presence of different variants (all missense mutations) are indicated. In ancestral nodes, these phenotypes or variants were inferred with ASR. To illustrate relevant transitions, the size of the sphere indicates whether ...
The results indicate that essential oils from Pakistani spices can be pursued against multidrug resistant bacteria.Peer Review reports Background Resistance of pathogens to antimicrobial compounds has lethal effects as the development of drug resistance outpaces the development of new drugs. Infectious ...
Accordingly, the aim of this study was to establish a medication regimen to prevent drug resistant bacteria. To determine a rational therapeutic guideline, integrated pharmacodynamics and pharmacokinetics parameters were based to predict dose and dosage interval of enrofloxacin in grass carp ...
(MDR) is an international, peer-reviewed journal that covers the global threat and spread of multi-drug resistant clones of major pathogens that are widely documented in hospitals and the scientific community, the efforts to develop novel therapeutic strategies targeting the drug-resistant bacteria, ...
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The soil resistome: a critical review on antibiotic resistance origins, ecology and dissemination potential in telluric bacteria. Environ. Microbiol. 17, 913–930 (2015). PubMed Google Scholar Finley, R. L. et al. The scourge of antibiotic resistance: the important role of the environment. ...