drug efflux pumps extrude drug molecules outside the cells. The majority of the activity of drug efflux pumps in bacteria occurs through the activity of ion motive force; however, many pumps use ATP hydrolysis as a driving factor as well. Some of the major drug efflux transporter families...
lnc-RP11-536 K7.3interacts with SOX2, initiating the transcriptional activation of USP7 mRNA. This activation of USP7 facilitates the deubiquitination of hypoxia-inducible factor (HIF-1α), thereby
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Drug resistance is mainly responsible for cancer recurrence and poor prognosis. Epigenetic regulation is a heritable change in gene expressions independent of nucleotide sequence changes. As the common epigenetic regulation mechanisms, DNA methylation, h
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