To advance the series of novel molecules from conception to evidence of antiviral activity, the scientists have gathered support, guidance, expertise and resources from researchers around the world within a year. The article reported that researchers have built an alternative template for drug-discovery...
The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: All authors are employees of Bayer AG. Acknowledgements We thank S. Röhrig, H. Briem, and G. Mogk for helpful discussions, and R. Webster, A. Cleve, M. Follma...
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The corresponding part from the HIV-RT/DNA-RNA/dATP (HIV-RT residue 1 to 320) is shown in gray surface representation for comparison. Apart from the N-terminal domain partially protruding out of the template’s surface envelope, all the other domains (“thumb”, “fingers” and “palm” ...
To further validate this assay for detecting mecA, vanA, and vanB genes, the DNA extracted from clinical isolates was used as the template DNA. The detection of the target gene for clinical isolates was confirmed using the one-step multiplex qPCR assay, and the results of MRSA, MSSA, VRE,...