On the other hand, the idea of verification of consumers’ ADE reports by HCPs could be a barrier. R1: “Whether a verification is required before it was reported to the TGA, I think that might not be ideal because it could discourage people from perhaps reporting to the TGA directly.”...
To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc-nd/4.0/. Reprints and permissions About this article Cite this article Khanna, A., Adams, J., Antoniades, C. et al. Accelerating Parkinson’s Disease drug development with federated learning approaches. npj ...
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To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativeco mmons.org/publicdomain/zero/1.0/) applies to the data made ...
To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the ...
Acute promyelocytic leukemia (APL), which was once considered one of the deadliest types of leukemia, has become a curable malignancy since the introduction of all-trans retinoic acid (ATRA) and arsenic trioxide (ATO) as clinical treatments. ATO, which h
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(n = 6). Second, we did not verify the mechanism after proposing the potential mechanism. Regarding the potential mechanism of this study, we can use liver gene knockout technology for verification, but liver gene knockout technology is not currently popular, and it is difficult to ...
We integrated and processed multiple related open-source datasets through a combination of automatic processing and manual verification (Fig. 1). The source datasets utilized in this study were SKEMPI v2.0, SAbDab (by July 25th, 2024), PDBbind v2020, Affinity Benchmark v5.5, and ATLAS. The cr...
There is a lack of effective therapeutic strategies for amyotrophic lateral sclerosis (ALS); therefore, drug repurposing might provide a rapid approach to meet the urgent need for treatment. To identify therapeutic targets associated with ALS, we conduct