Grapefruit juice ingested concurrently with several classes of drugs can profoundly influence drug effects and toxicity. Fatal interactions have been reported. Grapefruit juice inhibits cytochrome P450 3A (CYP3A) enzymes and may inhibit cytochrome P450 1A2 (CYP1A2) enzymes.2,5 This can inhibit ...
Grapefruit juice and grapefruit product consumption have potential health benefits; however, their intake is also associated with interactions with certain drugs, including calcium channel blockers, immunosuppressants and antihistamines. The primary mechanism through which interactions are mediated is mechanism...
Use our drug interaction checker to quickly identify multi-drug interactions, including with alcohol, food, supplements, and diseases.
Dangerous Interactions When Drinking Alcohol Alcohol is a common substance that may interfere with a variety of drugs. Interactions with drugs may cause nausea, vomiting, fainting, headaches, dizziness, changes in behavior, and blood pressure changes. The effects of many other drugs are increased whe...
Lovastatin and simvastatin also have drug interactions with grapefruit juice, and you should not drink grapefruit juice at all with these medications.The drug maker of atorvastatin suggests that people taking this drug avoid large quantities of grapefruit juice (more than 1 quart per day). Always...
Grapefruit juice and grapefruit product consumption have potential health benefits; however, their intake is also associated with interactions with certain drugs, including calcium channel blockers, immunosuppressants and antihistamines. The primary mechanism through which interactions are mediated is mechanism...
Learn about potential drug interactions you may be exposed to. Drug interactions can occur with prescription drugs, OTC medications, grapefruit and other foods, vitamins, herbs, supplements, and even laboratory tests.
Seediscussions,stats,andauthorprofilesforthispublicationat:https://.researchgate.net/publication/12328028 Drug–GrapefruitJuiceInteractions ArticleinMayoClinicProceedings·October2000 ImpactFactor:6.26·DOI:10.4065/75.9.933·Source:PubMed CITATIONS 198 READS 290 2authors,including: GarvanCKane MayoFoundationfor...
Drug Interactions with Grapefruit Juice Concomitant intake with grapefruit juice increases the concentrations of many drugs in humans. The effect seems to be mediated mainly by suppression of the... Professor,Dr,med,... - 《Drug Safety》 被引量: 779发表: 1998年 Grapefruit juice–drug interact...
drugs with grapefruit juice, and to discuss the mechanism and causative agents in such interactions.A MEDLINE search covering the period 1989-2002 was performed to identify review articles, studies, and case reports referencing the potential interaction of grapefruit juice with several classes of ...