Drug Interaction CategoriesDescriptions Contraindicated Never use this combination of drugs because of the high risk of dangerous interaction Serious Potential for serious interaction; regular monitoring by your doctor is required or alternate medication may be needed Significant Potential for significant intera...
When that happens, it's called adrug interaction. It could make your medication stop working, become less effective, or too strong. It could also trigger side effects. The more you learn about drug interactions, the better you'll be able to avoid them. Here's what you need to know. ...
The platelet reactivity index measured by the flow cytometric VASP method was 36.8% lower when clopidogrel was administered in conjunction with fluoxetine. 展开 关键词: Clopidogrel resistance Drug-drug interaction Fluoxetine Platelet pharmacology DOI: 10.1111/fcp.12024 年份: 2013 ...
Smoking behavior and dosage (100, 150, 200 mg) have significant impact on concentration/dose ratio, age, weight and serum levels; whereas no metabolic interaction between trazodone with citalopram or fluoxetine could be revealed. Thus, a 2-way approach in antidepressant treatment with trazodone and...
This system classifies drug-drug interactions based on the management of the interaction ( Table ).[3] Potential Interactions With Simvastatin Simvastatin is a substrate of the CYP3A4 isoenzyme and undergoes extensive first-pass metabolism.[3] Although trazodone is cleared primarily by the kidneys,...
Herb-drug interaction of silymarin or silibinin on the pharmacokinetics of trazodone in rats. Herb-drug interaction of silymarin or silibinin on the pharmacokinetics of trazo- done in rats[J]. Chemico-Biological Interactions,2009 (182):227... JC Chang,YT Wu,WC Lee,... - 《Chem Biol Interact...
Herb-drug interaction of silymarin or silibinin on the pharmacokinetics of trazodone in rats. Silymarin, one of the most popular herbal medicines, has been widely used for its hepatoprotective effects. This study investigates the effects of repeated... JC Chang,YT Wu,WC Lee,... - 《Chem Biol...
The drug classes most used were antidepressants, cardiovascular agents, and lipid-modifying agents, with a decrease in use after 12 months of surgery. Before surgery, it was found that more than half of the patients had at least one drug interaction in their therapeutic regimen. Of these, ...
Small NLGiamonna KA Interaction between warfarin and trazodone. Ann Pharmacother 2000;34734- 736PubMedGoogle ScholarCrossref 35. Yates RAWong JSeiberling MMerz MMarz WNauck M The effect of anastrozole on the single-dose pharmacokinetics and anticoagulant activity of warfarin in healthy volunteers....
The presence of comorbid conditions and associated polypharmacy further complicate the framework: most patients with AUD have tried or are actively using other drugs, and more than 33% of them present a drug use disorder [15]. Thus, the drug–drug interaction is an important and underestimated ...