The University of Liverpool provides an online tool to check for interactions. Many people with HIV need to take medicines to treat other health conditions. Taking two or more different drugs together may change the effectiveness or side effects of one or more of the drugs. This is nearly alwa...
Ritonavir, a protease inhibitor, is a known CYP450 inhibitor that is commonly used in the treatment of HIV 1 . Iatrogenic Cushing's syndrome is caused by exposure to glucocorticoids and may be promoted by interaction with additional drugs that result in hypothalamic-pituitary adrenal axis ...
DAA interactions in the HIV/HCV co-infected patient are largely extrapolated from drug-drug interaction studies with commonly used antiretrovirals. These studies then inform the selection of permitted antiretroviral regimens in phase II and III DAA clinical studies in HIV/HCV co-infection. We review ...
Interestingly, there is a specialised database commonly used to determine DDIs of HIV medicines in HIV community. Liverpool HIV interaction database focused mainly on HIV drugs was selected into this study in order to determine the ability and agreement of the three electronic databases in ...
drug interaction boosting agent nucleoside chronic obstructive pulmonary disease (COPD) The study endpoint was the presence of a DDI between two drugs (ARV with ARV, or ARV with non-ARV drugs, prescribed for other conditions than HIV). Interactions were identified as such if they yielded a “do...
is relevant, reliable and up-to-date. HIV iChart can be used on a hospital ward or in a clinic, in primary-care units, health centres and the community. In addition to the HIV drugs interaction website, this new tool will increase awareness of how to manage the disease more effectively...
University of Liverpool. COVID-19 drug interaction. Available at: https://www.covid19-druginteractions.org/checker. Accessed 9 Oct 2022. Lemaitre F, Grégoire M, Monchaud C, Bouchet S, Saint-Salvi B, Polard E. Management of drug-drug interactions with nirmatrelvir/ritonavir in patients tre...
reported the interaction between heparin and SARS-CoV-2 spike S1 protein receptor binding domain (Mycroft-West et al., 2020). Another study results are suggesting that heparin is found to be effective in COVID-19 management beyond anticoagulant effect through its pleiotropic activity (Gozzo et al...
(NHS) is doing screening tests for some patients being prescribed cancer and HIV drugs. A report on March 29th by the British Pharmacological Society (BPS) and the Royal College of Physicians (RCP) proposed widening that testing to cover the 40 drugs among the 100 most-prescribed that are ...
N. Dissecting the Molecular Mechanism of IVIg Therapy: The Interaction between Serum IgG and DC-SIGN is Independent of Antibody Glycoform or Fc Domain. J. Mol. Biol. 425, 1253–1258 (2013). Article CAS Google Scholar Anthony, R. M., Kobayashi, T., Wermeling, F. & Ravetch, J. V....