SummaryWith the increasing use of intravenous bisphosphonates in oncological settings, osteonecrosis of the jaw is now a more common and often devastating complication which, in an advanced stage, significantly impacts the quality of life. Since management and therapy of osteonecrosis present major ...
SummaryWith the increasing use of intravenous bisphosphonates in oncological settings, osteonecrosis of the jaw is now a more common and often devastating complication which, in an advanced stage, significantly impacts the quality of life. Since management and therapy of osteonecrosis present major challe...
Drug-induced jaw osteonecrosis 来自 Semantic Scholar 喜欢 0 阅读量: 36 作者: G Donati 摘要: Medication-related osteonecrosis of the jaw (MRONJ), an adverse reaction to medication, has been reported since 2002, at first in cancer patients with bone metastases treated intravenously with pamidronate...
Genomewide Pharmacogenetics of Bisphosphonate-Induced Osteonecrosis of the Jaw: The Role of RBMS3 Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a serious adverse drug reaction. We conducted a genomewide association study to search for genet... P.,Nicoletti,V.,... - 《Oncologist》 ...
In addition to the adverse drug reactions discussed in detail in this article, there are a number of other relatively common reactions, including clozapine-induced agranulocytosis, bisphosphonate-induced osteonecrosis of the jaw (BONJ) and renal toxicity, that are important clinical problems. Clozapine...
What drugs cause osteonecrosis of the jaw? What are some medicines for Lewy body dementia? What is alcohol withdrawal delirium? What medications can affect platelet function? What medications are used to treat macular edema? What antiretroviral drugs worsen osteoporosis?
As the proportion of drug-induced cases of CC is considered to be higher in Japan than in Europe and the United States6, it is important to avoid risk factors for MC treatments; however, data regarding causative drugs are controversial20. The spontaneous reporting system (SRS) is a valuable...
Geng CJ, Liang Q, Zhong JH, et al. Ibandronate to treat skeletal related events and bone pain in metastatic bone disease or multiple myeloma: a meta-analysis of randomised clinical trials. BMJ Open. 2015;5(6):e007258. Ruggiero SL. Bisphosphonate-related osteonecrosis of the jaw: an overview...
In the other hand it has adverse drug reactions mild to moderate which have reported but the mechanism still unclear such as hypocalcaemia and secondary hypophosphatemia, acute phase response (APR), renal toxicity, and osteonecrosis of the jaw (ONJ). Adverse drug reaction can cause harm to ...
osteonecrosis of jaw and subtrochanteric fractures.10Other osteoporosis therapies, such as oestrogen replacement therapy (ERT) and selective oestrogen receptor modulators (SERMs), inhibit osteoporosis by regulating osteoclast apoptosis but increase the risk of endometrial cancer, stroke and thromboembolism.7,...