The most common drug-induced movement disorders are caused by drugs that affect dopamine transmission in the brain: either levodopa or centrally acting dopamine receptor blockers (DRBA). DRBA cause three distinct patterns of movement disorder: acute dystonic reaction, withdrawal emergent syndrome, and ...
Parkinson's disease is a progressive neurodegenerative disorder associated with tremor, rigidity, and bradykinesia, as well as nonmotor symptoms including ... Q Maryka,B Tanuja,Z Danhui,... - 《International Review of Neurobiology》 被引量: 25发表: 2015年 Drug-induced movement disorders in chi...
Drug-induced parkinsonism is likely the most common drug-induced movement disorder and one of the most common nondegenerative causes of parkinsonism. Any medication that interferes with dopamine transmission may cause parkinsonism. The prototypical drugs are dopamine receptor blocking agents, specifically ...
Chlorpromazine, a phenothiazine derivative, is a first-generation antipsychotic drug that is used to treat acute and chronic psychoses including schizophrenia, manic episodes of bipolar disorder, and mental disorder induced by amphetamines. Chlorpromazine exerts potent anticholinergic, antidopaminergic, antihis...
Drug-induced action potential prolongation should be distinguished from prolongation arising from the variability of cell-to-cell beating with the use of positive and negative control compounds.55 As indicated above, other potassium channels in addition to h...
Dysarthria(speech disorder, slurred speech) Asthenia(weakness) Akathisia(restlessness) Muscle weakness Rigidity Muscle cramps Unsteadiness Accidental falls, injuries and fractures Extrapyramidal symptoms (drug-induced movement disorders) Tremor Convulsion/seizures ...
A typical antipsychotics: CATIE study, drug-induced movement disorder and resulting iatrogenic psychiatric- like symptoms, supersensitivity rebound psychosis and withdrawal discontinuation syndromes. Psychother Psychosom. 2008;77:69-77.Chouinard G., Chouinard V.A. Atypical antipsychotics. CATIE study, drug...
Drug Induced Movement Disorder: Case report and Literature Review These presentations usually involve basal ganglia, manifested with multiple neuropsychiatric disorders. We described a patient with acute onset schizophrenia, who... AT Alshomrani,RM Shuqdar - 《Journal of Taibah University Medical Sciences...
Research concerned with drug-induced depression is characterised by a number of methodological complications. These include differing definitions of depression, including depression defined as a symptom, a syndrome, or by diagnostic criteria for a specific mental disorder. In addition, patients undergoing ...
Valsartan Aluminum trichloride (AlCl3) and d-galactose (d-gal)-induced experimental sporadic dementia of Alzheimer's type in mice Improves the cholinergic activity, restores SOD and GSH-Px activities, and reduces MDA level in cortex and hippocampus [44] Irbesartan AD mouse model Activation of PPAR...