No definitive diagnosis was made at the time of discharge; however, cessation of hydralazine was noted to coincide with the last of the patient's fevers. Following the discharge, her anti-histone antibodies returned a positive result, and the diagnosis of drug-induced lupus was made with ...
Drug-induced lupus is a syndrome resembling mild systemic lupus erythematosus which can complicate treatment with certain apparently unrelated therapies. The most common individual agents are procainamide and hydralazine. Drugs less frequently associated with the disease are chlorpromazine, isoniazid, methyldopa...
lupus requires identification of a temporal relationship between drug administration and symptom development, and in traditional drug-induced lupus there must be no pre-existing lupus. Resolution of symptoms generally occurs after cessation of the drug. In this review, we will discuss those drugs that...
Drug-induced lupus (DIL) is an autoimmune phenomenon where a drug exposure leads to the development of systemic lupus erythematosus (SLE) like clinical features. DIL is a clear example of an environmental trigger leading to the development of lupus in a genetically susceptible individual. Hydralazine...
Systemic lupus erythematosus (SLE) induced by drugs, primarily hydralazine and procainamide, is reviewed and compared with idiopathic SLE, and the use of these drugs in patients with idiopathic SLE is discussed. The etiology of SLE is unclear, but genetic predisposition is an important factor. Alth...
9.5. Autoimmune disease – idiopathic and drug-induced systemic lupus erythematosus (SLE) SLE is an autoimmune disease that can be expressed with systemic symptoms or limited to one specific organ, e.g., skin, kidney, blood vessels. The serum profile is characterized by two main types of autoa...
We suggest use of steroids early in drug-induced lupus erythematosus, if associated with severe pericarditis with any question of pericardial tamponade (even... Greenberg,Joseph,H. - 《Jama the Journal of the American Medical Association》 被引量: 9发表: 1972年 Adalimumab-Induced Lupus Serositis...
Drug-induced dermatomyositis (DIDM) is a rare and underestimated variant of dermatomyositis (DM) characterized by muscle damage and skin rash and related to certain drug exposure. The spectrum of drugs causing DIDM has evolved over time, originally implicating hydroxyurea, penicillamine, and statins ...
Abstract 13315: Recurrent Cardiac Tamponade Due to Minoxidil Associated Drug Induced Lupus Erythematosus in approximately 3-5% of patients receiving minoxidil therapy, which could be attributed to volume overload associated with underlying renal insufficiency. Besi... M Juarez,J Benjanuwattra,AH Ramos,...
in a period ranging from several months or years after the resolution of the syndrome, and some are similar to those seen after bone marrow transplant. The related conditions include diabetes mellitus type 1, lupus erythematosus, Hashimoto’s thyroiditis, enteropathy, sclerodermiform lesions, GVHD,...