药物相互作用(DDI)指一种药物的效应受到另一种药物、食物或者环境的影响而发生改变的现象。在临床工作中,通常指一种药物的药代动力学或药效动力学被另一种药物改变。因药物相互作用而被召回的上市新药,已经有多个先例(如2001年因DDI引起横纹肌溶解的降脂药西立伐他汀、2000年出现尖端扭转型室速的胃药西沙比利等),...
Other types of drug action Certain drugs act without engaging in any direct interaction with the components of the cell. An example ismannitol, an inert polysaccharide that acts purely by its osmotic effect. This drug increasesurineproduction markedly because it interferes with water reabsorption by ...
4 Types A drug interaction can be defined as an interaction between a drug and another substance that prevents the drug from performing as expected. There are 4 types of drug interactions include: interactions of drugs with other drugs (drug-drug interactions), as well as drugs with food (dru...
There arethree typesof drug interactions: Drug-condition interaction:This is when having a certain medical condition can affect the way a medication works. This can also refer to when a medication has negative effects on a person’s medical condition. Drug-drug interaction:This is when one medic...
Drug Interaction Facts, Drug-Reax, Lexi-Interact, Pharmavista, Stockley’s Drug Interactions, The Medical Letter and Vidal ,常用于处方 (用 药医嘱)的检查,以发现最具临床相关性的DDI Drug-Reax (Micromedex®) Lexi-Interact Pharmavista 信息系统识别DDI 此外,一些其它的数据库也列出了已知的DDI,包括:Da...
What is a drug interaction? There are 3 main types of drug interactions to watch for: Drug-drug interactions:This is the most common type of drug interaction and involves one drug interacting with another. If you take many medicines, your chances for this type of interaction increases. For ...
相关概念相互作用对(interactionpair)能够引起药物效应变化的两个药物目标药物(objectdrug,orindexdrug)在联合用药中，药效发生变化的药物相互作用药物，促发药物(interactiondrug,orprecipitatingdrug)在联合用药中，引起其他药物发生变化的药物 2药物相互作用的研究对象 药物在体外和药物在体内的相互作用药物...
相关概念相互作用对(interactionpair)能够引起药物效应变化的两个药物目标药物(objectdrug,orindexdrug)在联合用药中，药效发生变化的药物相互作用药物，促发药物(interactiondrug,orprecipitatingdrug)在联合用药中，引起其他药物发生变化的药物 2药物相互作用的研究对象 药物在体外和药物在体内的相互作用药物...
The two major types of MAOI drug–drug interaction are the serotonin syndrome and the hypertensive (also called hyperadrenergic) crisis.102 Hypertensive Crisis Hypertensive crisis is an emergency characterized by an abrupt elevation of blood pressure, severe headache, nausea, vomiting, and diaphoresis;...
Drug-Drug Interaction (DDI)acute hepatic porphyria (AHP)acute intermittent porphyria (AIP)delta aminolevulinic acid synthase 1 (ALAS1)hemeThe evaluation and management of combination drug therapy assumes much importance especially where the drugs are used for prolonged time-period. Management of HIV/...