drug delivery systemNANOBUBBLESTHERANOSTICSULTRASOUNDUltrasound(US)medical technology is widely used due to its advantages of safety,speed,and low cost.With the rapid development of biomedical nanotechnology,micro/nanobubbles,as US contrast agents,are not only valuable in US imaging diagnosis but also show...
Therefore, other structures used for drug delivery, such as nanobubbles [3], labelled small molecules [4], proteins [5], RNA [6], oligonucleotides [7], and antibodies [8], were not considered in this review. 2. Definitions 2.1. Image-guided drug delivery The definition of image-guided ...
and targeteddelivery. Although some research on nanoencapsulation of GTP for delivering to the target tissue has been done, still much work is needed to develop a perfect delivery system for it. In future, we need to select the best nanovehicle for targeted delivery of GTP based ontoxicokinetic...
External stimuli for controlled nanoscale drug delivery usually refer to ultrasounds, temperature, light and magnetic field. These stimuli generally do not rely on the tumor pathology and microenvironment. Internal stimuli, also known as endogenous or biological stimuli, primarily effect on the impaired ...
Preparation and Evaluation of the In situ Gel-forming Chitosan Hydrogels for Nasal Delivery of Morphine in a Single Unit dose in Rats to Enhance the Analgesic Responses. July 25, 2023 [MEDLINE Abstract] Ultrasound-Mediated PLGA-PEI Nanobubbles Carrying STAT6 SiRNA Enhances NSCLC Treatment via Repol...
Over the past few decades, applications of ultrasound (US) in drug delivery have been documented widely for local and site-specific release of bioactives in a controlled manner, after acceptable use in mild physical therapy for tendinitis and bursitis, and for high-energy applications in fibroid ...
Herein, we propose a Carbopol hydrogel-based oxygen nanodelivery "nanohyperbaric" system as a wound dressing material for an enhanced wound healing process. Oxygen nanobubbles (ONBs) were used to supply oxygen, and collagenase was added in the gel as a drug model. Both oxygen and collagenase wo...
based drugs. This Review describes how specially designed cavitation nuclei in the form of solid, liquid or gas particles can enable the triggered release of drugs, promote the permeabiliziation of challenging biological barriers and enhance drug delivery through tissue regions where diffusion alone ...
Pulmonary drug delivery systems are based on inhalation therapy and utilize lung properties such as high absorptive surface area and intense blood supply. Some challenges to this technique include low drug dosages, poor drug stability, and the low efficiency of the inhalation practice [6]. ...
breakage of chemical bonds between drug and carrier[62,63]. Nanobubbles with good biological compatibility and stability allow gas retention, which can not only improve the contrast and clarity of ultrasound assistance, but also enhance the delivery of large molecules into cells[64]. In addition, ...