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This paper draws on data collected as part of a larger research project aiming to inform the implementation of DCS in Scotland, delivery of which is planned in three Scottish cities (Aberdeen, Dundee, and Glasgow) as part of a wider suite of harm reduction measures in response to current lev...
The role of methadone in drug-related deaths in the west of Scotland Addiction, 98 (2003), pp. 995-1002 View in ScopusGoogle Scholar 91 N. Shah, S.L. Lathrop, M.G. Landen Unintentional methadone-related overdose death in New Mexico (USA) and implications for surveillance, 1998-2002 Addi...
We also identified four key motifs,JUN,HIC1,NFKB1_REL_RELA, andTFAP2B, putatively controlling programmed cell death of statin-treated cells as off-target effects (Supplementary Fig.5).JUNandNFKB1_REL_RELAare well-known regulators of apoptosis, whereasHIC1have been reported as a hyper-methylat...
(e.g. alcohol), and/or illicitly obtained controlled drugs, meaning the cohorts examined were often in the context of polydrug use. One study defined the outcome as death by unintentional overdose, according to post-mortem medical examination records [72], while one examined people hospitalised ...
Abstract Mammalian sterol and lipid metabolism depends on a large number of highly evolved biochemical and histological processes responsible for the absorption, distribution and steady-state anabolic/catabolic handling of these substances. Lipoproteins are complex polymolecular assemblies comprising phospholipids...
It is likely that the magnitude of risk reduction produced by lipid-lowering therapy is proportional to the degree of cholesterol lowering achieved, which is an important consideration when selecting an agent and deciding the dosage to use. The results of several multicentre comparative trials have ...