(CSA), which is Title II of theComprehensiveDrug Abuse Prevention and Control Act of 1970. The CSA established a classification system with five schedules to identify drugs based on their potential for abuse, their applications in medicine, and their likelihood of producing dependence. The DEA is...
Astellas Issues Recall of One Lot of Prograf 0.5 mg and One Lot of Astagraf XL 0.5 mg Because Bottles Shipped to U.S. May Contain Empty Capsules New Drug Approvals Tevimbra Approved in U.S. for First-line Treatment of Gastric and Gastroesophageal Junction Cancers in Combination with Chemoth...
Classification of drugs using the ATC system The ATC system is the WHO classification system for therapeutic drugs. The system has a hierarchical structure, where the topmost level,‘level 1—Anatomical main group’, specifies the target organ or tissue, and the lowermost level, ‘level 5—chemic...
The NHIF database contains information on the prescribed and dispensed drug name, date of prescription and dispensing, International Classification of Diseases (ICD-10) diagnosis codes, anatomical-therapeutic-chemical (ATC) code of the drug, number of packs dispensed, number of tablets in each ...
Classifying genes into CNA genotype-dependent/independent in-cis, in-trans gene types based on copy number alterations: the input data for gene classification is differentially expressed genes in scRNA-seq data between two clones that were inferred using clonealign and copy number alteration between ...
Influence of number of drug targets on classification performance The number of drug target proteins per drug varies considerably, ranging from 1 to 26 for the Guney reference set (mean of 3.5, median of 2), and from 1 to 51 for the EMC reference set (mean of 3.4, median of 2). To ...
Super.FELT consists of three stages, namely, feature selection, feature encoding using a supervised method, and binary classification of drug response (sensitive or resistant). We used multi-omics data including mutation, copy number aberration, and gene expression, and these were obtained from cell...
For example, the model in [11] uses chemical structure and protein sequence sim- ilarity as basis of its classification rules, and the model in [4] produces less satisfactory results when the modes of interaction between chemicals and proteins are unknown. This is problematic because databases ...
Association between expression of random gene sets and survival is evident in multiple cancer types and may be explained by sub-classification. PLoS Comput Biol. 14, e1006026 (2018). ADS PubMed PubMed Central Google Scholar Shukla, S. et al. Development of an RNA-Seq Based Prognostic ...
7and the alarming rise of antifungal drug resistance4,8,9.Candidaspecies are a major cause of severe hospital-acquired infections1, prompting the classification of some species (Candida auris,Candida albicans,Candida glabrata,Candida tropicalisandCandida parapsilosis) as critical or high-priority targets...