Celebrex is an NSAID that belongs to the COX-2 inhibitor class. Drugs under this classification work by inhibiting the production of an enzyme called Cyclooxygenase-2 (COX-2). COX-2 is one of the many enzymes that trigger formation of prostaglandin which is thought to be the cause of inflam...
Interaction classification and severity The drug affected and the type of interaction (potentiation, inhibition, or no effect) were noted. Interactions that potentiated or inhibited the effect of warfarin were further rated as major, moderate, minor, or nonclinical. Major potentiation was defined by ...
Interaction classification and severity The drug affected and the type of interaction (potentiation, inhibition, or no effect) were noted. Interactions that potentiated or inhibited the effect of warfarin were further rated as major, moderate, minor, or nonclinical. Major potentiation was defined by ...
The general classification of drug targets was shown in Figure 2A. The target based drugs often modulate the function of the proteins, or total inhibition in case of pathogens. Antimicrobial drugs are mostly target based and the targets should (i) be pathogen specific; (ii) essential and ...