and which can then invade adjoining parts of the body to spread to other organs” in a process known as “metastasis”. The initial growth or swelling is referred to as a tumor or neoplasm. Importantly, while
The World Health Organization (WHO) defines cancer as a group of diseases caused by the rapid proliferation “of abnormal cells that grow beyond their usual boundaries, and which can then invade adjoining parts of the body to spread to other organs”...
Cyclophosphamide (CP) is an important anticancer drug which belongs to the class of alkylating agent. Cyclophosphamide is mostly used in bone marrow transplantation, rheumatoid arthritis, lupus erythematosus, multiple sclerosis, neuroblastoma and other types of cancer. Dose-related cardiotoxicity is a ...
a, The 15-passage strategy using the pneumonia model in both immunocompetent and neutrophil-depleted mice. Neutrophil depletion was induced by two doses of cyclophosphamide at 72 and 24 h before infection. At the time of infection,A. baumanniiATCC 17978 was oropharyngeally inoculated into mice ...
Ifos is a chemotherapeutic agent chemically related to the nitrogen mustards and a synthetic analog of cyclophosphamide. Ifos is 3-(2-chloroethyl)-2-[(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide. The molecular formula is C7H15Cl2N2O2P and its molecular weight is 261.1...
Many chemotherapy drugs such as 5-FU, and its combination of cyclophosphamide, used to enhance the body's anti-tumor activity, therefore, polysaccharides as anti-cancer drug development and use of the ideal. 翻译结果3复制译文编辑译文朗读译文返回顶部 ...
Many tumors have developed resistance against chemotherapy drugs, either through drug inactivation or by reducing action form. A major part of drug activation and inactivation takes place through the liver cytochrome P450 (CYPs) system [299,300]. For example, the anticancer prodrug cyclophosphamide (...
(16) 4 2 2 10 Vincristine 51, Doxorubicin 38, Methotrexate 35, Etoposide 30, Neutropenia 89, Thrombocytopenia 55, Anaemia 38, Mercaptopurine 27, Cytarabine 24, Ifosfamide 18, Cyclophosphamide Vomiting 8, Mucositis 8, Deranged Liver Function Tests 7, 15, Carboplatin 7, Vinblasti...
The rash may be more severe, and desquamation of the skin on the palms, soles and intertriginous areas has been reported in patients receiving etoposide as part of an HCT preparative regimen in combination with cyclophosphamide [77]. The addition of total body irradiation to etoposide in ...
tmClass cytotoxic drugs langbot Traditionally, as for allcytotoxic drugs, the manufacturer advises not to breastfeed whilst taking azathioprine. WikiMatrix Cyclophosphamide is a commoncytotoxic drugused in this manner, and is often used in conjunction with total body irradiation. ...