7. Goulooze, S.C., A.F. Cohen, and R. Rissmann, Olaparib.British Journal of Clinical Pharmacology, 2016. 81(1): p. 171-173. 8. Rucaparib, in Drugs and Lactation Database (LactMed®). 2006, National Institute of Child Health and Human Development: Bethesda (MD). 9. Zhang, J....
such as accessibility, short gestation time, and an extensive database of adverse findings and historical control data. A PPND study will also be conducted in non-human primate if a biologic is being tested and it is only active in non-hu...
Briggs’ Drugs in Pregnancy and Lactation Risk evaluation and mitigation strategies (REMS) Medication guides Natural products database Boxed warnings Manufacturer index Immunization schedules Patient assistance program information Additional information links ...
Briggs’ Drugs in Pregnancy and Lactation Risk evaluation and mitigation strategies (REMS) Medication guides Natural products database Boxed warnings Manufacturer index Immunization schedules Patient assistance program information Additional information links ...
M. et al. The UCSF-FDA TransPortal: a public drug transporter database. Clin. Pharmacol. Ther. 92, 545–546 (2012). CAS PubMed Google Scholar Zamek-Gliszczynski, M. J. et al. ITC recommendations for transporter kinetic parameter estimation and translational modeling of transport-...
scheme shown in Figure 9-1). As such, a PPND study is used to assess the effects of test material on pregnancy, during lactation, and throughout the development and sexual maturity of the offspring. The latter includes the assessment of learning and memory, neuropsychology and functional behav...
ductulitis and marked cholestasis [55]. Oscanoa et al. also investigated VigiBase, the WHO pharmacovigilance database that records all individual case safety reports (ICSRs) from over 130 nations about significant hepatic abnormalities linked to the use of ivermectin for adult patients with COVID-...
Osteoarthritis and Rheumatoid Arthritis The Melflam Phase 2/3 clinical trial database includes 10,122 OA patients and 1012 RA patients treated with Melflam 7.5 mg/day, 3,505 OA patients and 1351 RA patients treated with Melflam 15 mg/day. Melflam at these doses was administered to 661 ...
This article reviews which dermatologic drugs have been reported to interfere with contraceptive efficacy, which should be avoided, and which have the fewest contraindications for use during pregnancy and lactation. Corticosteroids and tretinoin are discussed in detail. Sources and guidelines for choices ...
8.2 LactationRisk Summary There are no data on the presence of Dysport® in human or animal milk, the effects on the breastfed infant, or the effects on milk production. The developmental and health benefits of breastfeeding should be considered along with the mother's clinical need for ...