In order to address that issue, a three-layer scaffold was designed with a PCL-chitosan layer on the sides and a polyvinyl alcohol (PVA)-metformin HCl in the middle. This development was evaluated in rats and showed a reduction in inflammation, smaller scar area, and an optimal modulation ...
prepared microballoons based on polyvinyl alcohol (PVA) and Eudragit® S using an emulsion-solvent diffusion technique [94]. Eudragit® S formed a mechanically strong film (shell) on the outer surface of the microballoons which ensured the stability of the system during solvent evaporation and...
Amgen and Genentech have pioneered small molecule inhibitor development against NIK using a propargyl alcohol as a common motif to access the hydrophobic site behind the gk (e.g., compounds 1 and 2; Figure 4), and a synopsis of their approach is covered comprehensively in a recent publication...