Presentation Title: Medication Discovery for Drug Addiction Treatment, and the Preclinical Pipeline at NIDAAcri, Jane B.Canadian Journal of Addiction
Substance Abuse and Rehabilitation Dovepress open access to scientific and medical research Open Access Full Text Article REVIEW Could the link between drug addiction in adulthood and substance use in adolescence result from a blurring of the boundaries between incentive and hedonic processes? This ...
Paula D. Gordon, Ph.D., “How Marijuana Use Affects the Brain & Becomes a Factor in Fueling Both Addiction & the Fentanyl and Opioid Crisis, Presentation to the Doctors Federation for the World”, Video Conference Series, October 8, 2023. Click Here Paula D. Gordon, “Why Marijuana Legali...
National Institute on Drug Abuse, Drug Abuse and Addiction: 25 Years of Discovery to Advance the Health of the People: The Sixth Triennial Report to Congress from the Secretary of Health and Human Services. Bethesda, Md National Institute on Drug Abuse1999; 4. Office of National Drug Control ...
11, NO. 2 Molecular Neurobiology of Drug Addiction 81 Table 1. Evidence Supporting a Role for Gi and Go in the Acute and Chronic Actions of Drugs of Abuse on the Mesolimbic Dopamine System 1. Direct inactivation of Gi/Go in the NAc regulates cocaine and heroin self-administration behavior....
Applying a multidisciplinary approach enables care teams to effectively address the presentation of patient symptomology in addition to keeping staff safe.
in the right individuals. The eventual development and approval of new drugs that block the actions of CRH in the brain will, it is hoped, provide important tools for the management of drug addiction. At the same time, basic preclinical research must continue to examine the neurobiological mecha...
Cocaine is low on the value ladder of rats: possible evidence for resilience to addiction. PLoS One 5: e11592. Caprioli D, Celentano M, Dubla A, Lucantonio F, Nencini P, Badiani A (2009). Ambience and drug choice: cocaine- and dependent evaluation can be generalized to all nonhedonic ...
Increased focus on addiction treatment and social support following hospital discharge has the potential to mitigate both the human and economic impacts of IDU-IE. Perspectives COMPETENCY IN SYSTEMS-BASED PRACTICE: The proportion of IE cases that are related to IDU continues to rise in tandem with ...
Because concurrent alcohol use is not necessary for disulfiram to have beneficial effects on cocaine addiction, an ALDH-independent me- chanism is likely. Furthermore, whatever the underlying molecular mechanism, why disulfiram treatment reduces cocaine use remains unclear; several human laboratory Neuro...