Drosophila melanogaster is a commonly utilized organism for testing hypotheses about inheritance of traits. There is a wide variety of mutants of Drosophila that demonstrate effectively both dominant and recessive traits, as well as autosomal and X-linked inheritance (Flagg, 2005; Winchester & Wejks...
Resistance to the cyclodiene insecticide dieldrin maps to a single gene (Rdl) on the left arm of chromosome III in Drosophila melanogaster (Meigen). The gene was further mapped by the use of chromosomal deficiencies to a single letter sub-region, 66F, on the polytene chromosome. The cross-...
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E. Using Drosophila melanogaster to map human cancer pathways. Nature Rev. Cancer 5, 626–639 (2005). Article CAS Google Scholar Ellisen, L. W. et al. TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms. Cell 66, ...
The development of a widely adopted cryopreservation method remains a major challenge in Drosophila research. Here we report a robust and easily implemented cryopreservation protocol of Drosophila melanogaster embryos. We present innovations for embryo p
Conclusion Taken together, our in vivo binding and gene expression data support a role for the Su(Hw) protein in maintaining a constant genomic architecture.Similar content being viewed by others CBP binding outside of promoters and enhancers in Drosophila melanogaster Article Open access 24 Novembe...
melanogaster, and FOXO3a in a cultured human cell line49,51. Considering that foxo was predicted to be a mediator of the MetR-responsive transcriptional shift (Fig. 4g), we hypothesised that MetR increases MsrA through the activation of foxo. Consistent with this, MsrA induction by the Met- ...
Mutations in genes encoding ribosomal proteins (RPs) have been shown to cause an array of cellular and developmental defects in a variety of organisms. In Drosophila melanogaster, disruption of RP genes can result in the 'Minute' syndrome of dominant, ha
Electrophoretic variants were first identified in Drosophila simulans by Courtwright (1967) who used them to map the structural gene. Both electrophoretic and null mutants have also been identified in Drosophila melanogaster by Dickinson (1970) who has mapped the structural gene at 3 − 56.6 ± ...
The Drosophila homolog of the mouse mammary oncogene int-1 is identical to the segment polarity gene wingless. 来自 NCBI 喜欢 0 阅读量: 281 作者:F Rijsewijk,M Schuermann,E Wagenaar,P Parren,D Weigel,R Nusse 摘要: We have isolated the Drosophila melanogaster homolog (D int-1) of int-1...