Drosophila fruit fly is an ideal model system to explore mechanisms of longevity and aging due to low cost, easy handling and maintenance, large number of progeny per adult, short life cycle and lifespan, relatively low number of paralogous genes, high evolutionary conservation of epigenetic ...
Definition The fruit fly Drosophila melanogaster has an established and successful record as a valuable genetic model system for studying complex biological phenomena. For example, several basic signaling pathways have been discovered in this organism, and a lot of progress on understanding the ...
Drosophila as a Model Organism for Investigating Molecular and Cellular Etiologies Underlying Complex Neurological Disorders in Humans The fruit fly Drosophila has been utilized as a powerful biological system to address fundamental questions concerning neurological disorders in humans, si... YH Koh - Jour...
and likely some neurodegenerative diseases.Drosophila melanogaster is a well established model organism,which is widely used in various areas of biological research,and is fast adopted as a new platform for metal studies.Here we reviewed the progress of using Drosophila in metal research,including ...
: Use of Drosophila as a Model Organism in Neuropsychopharmacology Research Anjana S Narayanan1 and Adrian Rothenfluh*,1,2 1Department of Psychiatry, UT Southwestern Medical Center, Dallas, TX, USA; 2Program in Neuroscience, UT Southwestern Medical Center, Dallas, TX, USA Neuropsychiatric ...
Drosophila melanogaster as a Promising Model Organism in Toxicological Studies: A Mini Review The common fruit fly, Drosophila melanogaster, has been extensively studied for decades. In effect, it was introduced as a decisive model in biology about a century ago. The fly shares several basic biolog...
Sci. 2009, 10, 407-440; doi:10.3390/ijms10020407 Review OPEN ACCESS International Journal of Molecular Sciences ISSN 1422-0067 www.mdpi.com/journal/ijms Drosophila melanogaster as a Model Organism of Brain Diseases Astrid Jeibmann * and Werner Paulus Institute of Neuropathology, Domagkstraße ...
These features represent the core of a platform—into which other features, such as well-established genetic approaches in Drosophila may be incorporated—for mechanistic investigations in a model organism of clinical or pharmaceutical relevance.
1,726 Views 1 CrossRef citations to date 0 Altmetric Review Exploring the versatility of Drosophila melanogaster as a model organism in biomedical research: a comprehensive review Ayomide Victor Atoki, Patrick Maduabuchi Aja, Tijjani Salihu Shinkafi, Erick Nyakundi Ondari, Adekunle Is...
Using a Hox protein partnership as a test case, we investigated the suitability of BiFC for the study of protein interactions in the livingDrosophilaembryo. Importantly, all BiFC parameters were established with constructs that were stably expressed under the control of endogenous promoters. Under thes...