Association between the A1 allele of the DRD2 gene and reduced verbal abilities in adoles- cence and early adulthood. J Neural Transm 2010;117:827-30.Beaver KM, Delisi M, Vaughn MG, Wright JP (2010) Association between the A1 allele of the DRD2 gene and reduced verbal abilities in ...
Polymorphisms in dopaminergic genes may influence cigarette smoking by their potential impact on dopamine reward pathway function. A1 allele of DRD2 gene is associated with a reduced dopamine D2 receptor density, and it has been hypothesised that A1 carr
DRD2gene. 【Keywords】DepressionDRD2 GeneMutationHRM 抑郁症以情绪低落、兴趣减低、悲观厌世、思维迟1对象与方法 缓、睡眠饮食差等为主要表现,严 重者可出现自杀念头1.1对象选择2006—2010年在山东省精神卫生 中和行为,多数患者反复发作。在精神疾病中,抑郁症的心住院的抑郁症患者(以下简称患者)238例,其中男 发病率...
drd2 haplotypes containing the taqi a1 allele implications for alcoholism research 热度: dopamine transporter dat and receptor drd2 variants affect risk of lethal cocaine abuse a gene–gene–environment interaction 热度: 时珍国医国药2012年第23卷第9期 ...
found that rs6311 is in almost complete linkage disequilibrium with the 102 T/C SNP, a silent variant in exon 1 of the HTR2A gene [77]. The 102C allele has been associated with a diagnosis of SCZ [85] and with a poor response to clozapine [4, 5]. Given that these two SNPs are...
BACKGROUND: There is evidence that both reduction in P300 amplitude and the presence of the A1 allele are risk markers for alcoholism. We hypothesized that... SY Hill,J Locke,N Zezza,... - 《Biol Psychiatry》 被引量: 220发表: 1998年 The D2 Dopamine Receptor (DRD2) Gene and Family ...
In the literature analyses on the allele instead of the genotype level were common if the genotype frequencies for a given gene locus are skewed in the population. This is the case for the two SNPs under investigation in this study: As the homozygous A1/A1 variant of the DRD2/ANKK1 Taq ...
The A1 allele of the dopamine D2 receptor gene (DRD2) is associated with a reduced number of dopamine binding sites in the brain and with the increased lik... G E,Swan,A M,... - 《Pharmacogenomics Journal》 被引量: 189发表: 2005年 D2 dopamine receptor TaqI A alleles in medically il...
The A1 allele of the D2 dopamine receptor gene is associated with high dopamine transporter density in detoxified alcoholics. Alcohol Alcohol. 2001;36(3):262-26511373265PubMedGoogle ScholarCrossref 33. Jönsson EG, Nöthen MM, Grünhage F, Farde L, Nakashima Y, Propping P, Sedvall GC...
(A1/A2)多态性影响基因的表达,携带A1等位基因者脑内DRD2的数目 比携带A2等位基因者少〔6】。已有研究表明含.141I等位基因质粒的启动 子活性强于含.141D的质粒【7〕,,但是病例对照研究却发现.14lCl ns/Del和Ser 311 Cys突变与帕金森病的 1硕士学位论文 日廿吾 ...