The frequency of the A1 allele was foundADRIANMolecularTURNERMolecularJACOBMolecularLAWRENCEMolecularANDREWMolecularCHIH-HUIMolecularCHENMolecularCHRISTOPHERMolecularCOOKMolecularHUGHMolecularWileyAddiction BiologyTurner A, Lawrence J, Chen AC-H, Cook C, Gurling H: Frequency of the A1/A2 alleles of the D2 ...
Polymorphisms in dopaminergic genes may influence cigarette smoking by their potential impact on dopamine reward pathway function. A1 allele of DRD2 gene is associated with a reduced dopamine D2 receptor density, and it has been hypothesised that A1 carr
drd2 haplotypes containing the taqi a1 allele implications for alcoholism research 热度: dopamine transporter dat and receptor drd2 variants affect risk of lethal cocaine abuse a gene–gene–environment interaction 热度: 时珍国医国药2012年第23卷第9期 ...
BACKGROUND: There is evidence that both reduction in P300 amplitude and the presence of the A1 allele are risk markers for alcoholism. We hypothesized that... SY Hill,J Locke,N Zezza,... - 《Biol Psychiatry》 被引量: 220发表: 1998年 The D2 Dopamine Receptor (DRD2) Gene and Family ...
In the literature analyses on the allele instead of the genotype level were common if the genotype frequencies for a given gene locus are skewed in the population. This is the case for the two SNPs under investigation in this study: As the homozygous A1/A1 variant of the DRD2/ANKK1 Taq ...
(A1/A2)多态性影响基因的表达,携带A1等位基因者脑内DRD2的数目 比携带A2等位基因者少〔6】。已有研究表明含.141I等位基因质粒的启动 子活性强于含.141D的质粒【7〕,,但是病例对照研究却发现.14lCl ns/Del和Ser 311 Cys突变与帕金森病的 1硕士学位论文 日廿吾 ...
The A1 allele of the D2 dopamine receptor gene is associated with high dopamine transporter density in detoxified alcoholics. Alcohol Alcohol. 2001;36(3):262-26511373265PubMedGoogle ScholarCrossref 33. Jönsson EG, Nöthen MM, Grünhage F, Farde L, Nakashima Y, Propping P, Sedvall GC...
The Dopamine D3 receptor locus as a modifying gene in neuropsychiatric disorders --The A1 allele of the Taq I polymorphism of the dopamine D2 receptor (DRD2) gene has been earlier reported to occur in 69% of alcoholics, compared with 20... DE Comings,BG Comings,D Muhleman,... - 《Jam...
D2 dopamine receptor gene (DRD2) Taq1 A polymorphism: reduced dopamine D2 receptor binding in the human striatum associated with the A1 allele. The relationship between a dopamine D2 receptor genetic polymorphism at the Taq1 A locus and the level of D2 receptor binding was investigated in nor...
Hum dopamine receptor gene (DRD2) Taq1A polymorphism: reduced dopamine D2 Mol Genet 2006; 15: 3498–3507. receptor binding in the human striatum associated with the A1 allele. Pharma- 11 Huang W, Payne TJ, Ma JZ, Beuten J, Dupont RT, Inohara N et al. Significant cogenetics 1997; 7...