HLA—DRB.*1501等位基因的频率较普通人群高,对环孢菌 素A(CsA)治疗敏感且具有依赖性。由于HIA各等位基因存 在较大的种族和地域差异,在汉族人群中是否可以据此预测 CsA对从的疗效,目前报道较少。我们用PCR-SSO及PCR. SSP技术检测山东日照地区汉族从患者中该等位基因,观 ...
HLA—DRB1 ＊1501和DQB1 ＊0602与新疆哈萨克族HPV感染及食管癌发生的相关性研究
抗甲状腺药物引起Graves病病人白细胞减少与HLA-DRB1 ＊08032及-DRB1 ＊1501等位基因相关性 维普资讯 http://www.cqvip.com
HLA-DRB1*1501 and response to copolymer-1 therapy in relapsing-remitting multiple sclerosis Copolymer 1 (Cop-1) is a random synthetic amino acid copolymer, effective in the treatment of the relapsing-remitting form of MS (RRMS). In vitro and in vi... C Fusco,V Andreone,G Coppola,... ...
The HLA-DRB1*1501- and HLA-DQB1*0602-Tg mice (MHC-II-/-), and control non-HLA-DR15-relevant-Tg mice were immunized with a set of overlapping PLP peptides or with recombinant soluble PLP for induction of "humanized" MS-like disease, as well as for ex-vivo analysis of immunogenic/imm...
Severe morbidity was found in DRB11501-positive PPMS patients. This exploratory study raises new hypotheses for future research and emphasizes the need to investigate possible candidate genes other than HLA that may contribute towards heterogeneity in the course of the disease. 展开 关键词: Alleles ...
探讨HLADRB1*1501和DQB1*0602与新疆维吾尔、汉族妇女HPV感染及宫颈癌发生的相关性。PCR-SSP和PCR检测287例浸润性宫颈癌(维族192例,汉族95例)及297例正常宫颈组织(维族203例,汉族94例)中DRB1*1501和HLADQB1*0602的分布频率和HPV16DNA。维族HPV16阳性NILM组中DRB1*1501基因频率高于HPV16阴性NILM组(...
Carriers of the DRB1*1501 and APOE-epsilon4 allels did not reveal more severe disease progression, neither by the EDSS/years of duration nor by the TLA/years duration. This study was performed on a population-based sample in a genetically homogeneous Danish population but, due to the limited...