Major DQ8-restricted T-cell epitopes for human GAD65 mapped using human CD4, DQA1 * 0301, DQB1 * 0302 transgenic IA(null) NOD mice. Diabetes 1999; 48:469.Liu J, Purdy LE, Rabinovitch S, Jevnikar AM, Elliott JF. Major DQ8-restricted T-cell epitopes for human GAD65 mapped using human...
The recombination that occurred on the maternal chromosomes led to the unusual DR7-DQ8 haplotype characterized by the DRB1*0701-DRB4*01030102N-DQA1*0201-DQB1*0302 alleles. Because the patient had no HLA-identical sibling donor, a search for an unrelated hematopoietic stem cell donor was ...
Impaired binding of a DQ2 and DQ8-binding HSV VP16 peptide to a DQA1*0501/DQB1*0302 trans class II heterodimer. Tissue Antigens. 1999; 53:101- 105. [PubMed: 10082436]Reichstetter S, Kwok WW, Nepom GT. Impaired binding of a DQ2 and DQ8-binding HSV VP16 peptide to a DQA1*0501/ ...
Subjects carrying a monomer encoded by the HLA-DQA1 *05,DQB1 *02 (DQ2) or DQA1 *0301,DQB1 *0302 (DQ8) susceptible haplotypes may develop Coeliac DiseaseCeliac disease is an interesting and important condition for both clinicians and researchers. Clinicians deal with the daily problems of this...