As for bonds between lipid heads in liposomes, their cooperative destruction takes place at 41掳C for DPPC and 66掳C for DPPA liposomes. In the case of thermal distraction of DPPC liposomes, two so-called pre transitions peaks were observed before the main transition peak, which indicates that...
In this paper we present a systematic study of the morphology and composition of supported lipid bilayers (SLBs) formed by vesicle fusion using a wide variety of surface sensitive techniques that give information about the lateral as well as vertical structure and bilayer fluidity. SLBs of 1-pal...
Fig.1 The structure and corse-grained mapping of DPPC (a),DPPC bilayer in water (b),and the corse-grained mapping of water (c). 3 结果与讨论 3.1 脂均面积(Area Per Lipid,APL) APL为单个磷脂在脂质双层膜平面所占的面积,由式APL=<2ab/N>计算而得,其中a、b分别为DPPC双层膜平面的长和宽,N...
Importance of the tryptophans of gramicidin for its lipid structure modulating activity in lysophosphatidylcholine and phosphatidylethanolamine model membr... interaction of gramicidin analogs A, B, C (which have a tryptophan, phenylalanine and tyrosine in position 11, respectively) and tryptophan- N -...
DPPC (129Y83) is a zwitterionic glycerophospholipid commonly used in the formation of lipid monolayers, bilayers, and liposomes. 体内活性 将糖鞘脂类抗原并入含DPPC的脂质体中,能提高这些抗原在小鼠中的免疫原性[1]。 别名二棕榈酸磷脂酰胆碱, 129Y83, 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOL ...
We find that doping doses of polystyrene oligomers alter the thermal properties of DPPC, stabilizing the fluid lipid phase. They perturb the membrane structure and dynamics, in a concentration-dependent fashion. Eventually, they modify the mechanical properties of DPPC, reducing its bending modulus ...
The influence of 3-pentadecylphenol (PDP) on the structure and physicochemical properties of the lipid bilayers of DPPC liposomes was studied using ATR-IR and 31P NMR methods. On the basis of analysis of the bands assigned to the CH 2 stretching, CH 2 scissoring, C O stretching, and PO...
The interfacial curvature of the lipid micelle and water play important roles in the determination of micellar structure. The micellar structure is mainly controlled by the composition and the intermolecular interaction of amphiphilic molecules.
the influence of the interactions between different molecules on these states is much greater than the effect of the extent of the compression of monolayer.For xpac≤0.4,paclitaxel has a little influence on the structure of DPPC monolayer;for xpac0.4,the structure of DPPC monolayer is de-stroyed...
No interaction with the hydrophobic phospholipid bilayer domains was detected, revealing a poor capability of MTX to cross through lipid membranes to reach the interior compartment of a lipid bounded structure. These findings correlate well within vitro biological experiments on MTX cell susceptibility....