Two additional DPP-4 inhibitors are under review, and there are several others in clinical development. This article gives an overview on the mechanism of action of DPP-4 inhibitors and focuses on their development and their important physiological actions with regard to the treatment of type 2 ...
NA Thornberry,B Gallwitz.Mechanism of action of inhibitors of dipeptidyl-peptidase-4 (DPP-4).Best Pract Res Clin Endocrinol Metabol. 2009Thomberry N A, Gallwitz B,. Mechanism of action of inhib- itors of dipeptidyl peptidase4(DPP4) [ J]. Best Prac Res Clin Endocrinol Metabol, 2009,23...
2. Nancy A. Thornberry, Baptist Gallwitz. Mechanism of action of inhibitors of dipeptidyl-peptidase-4 (DPP-4)[J]. Best Practice & Research Clinical Endocrinology & Metabolism. 2009, 23(4):479-486 3. 周辛波. 关注长效口服降糖药—DPP4抑制剂[J].临床药物治疗杂志, 2015, 13(5):92-92...
SCHEEN AJ.DPP-4 inhibitors in the management of type 2 diabetes:a critical review of head-to-head trials[J].Diabetes Metab,2012,38(2):89-101. https://doi.org/10.1016/j.diabet.2011.11.001 本文引用 [1]摘要 [9] THORNBERRY NA,GALLWITZB.Mechanism of action of inhibitors of dipeptidyl-pep...
Dipeptidyl peptidase-4 (DPP-4) inhibitors are glucose-lowering drugs for type 2 diabetes mellitus (T2DM). We investigated whether evogliptin® (EVO), a DPP-4 inhibitor, could protect against diabetic cardiomyopathy (DCM) and the underlying mechanisms. Eight-week-old diabetic and obese db/db...
Differential chemistry (structure), mechanism of action, and pharmacology of GLP-1 receptor agonists and DPP-4 inhibitors. To review the pharmacology (absorption, metabolism, distribution, elimination, and contraindications) of incretin-based agents currently available and in regulatory review for the tre...
effect and have significant effects on a variety of patients who are ineffective in lowering blood glucose. Based on this, this article mainly reviews the mechanism of action of DPP4 inhibitors in the treatment of T2DM, analyzes the application and research progress of DPP4 inhibitors in T2DM, ...
This topic will review the mechanism of action and therapeutic utility of DPP-4 inhibitors for the treatment of type 2 diabetes mellitus. GLP-1 receptor agonists are discussed separately. A general discussion of the initial management of blood glucose and the management of persistent hyperglycemia ...
Through clinical case interpretation, brief introduction of the dipeptide base peptidase-4 (DPP-4) inhibitors/metformin fixed dose combination (fixed dosed combination, FDC) preparation of effectiveness, safety, and the mechanism of action were discussed. DPP-4 inhibitors could increase the endogenous ...
[Abstracq Through clinical case interpretation,brief introduction of the dipeptide base peptidase一4(DPP一4)inhibitors/metformin f ixed dose combination(f ixed dosed combination.FDC)preparation of ef fectiveness,safety,and the mechanism of action were discussed.DPP一4 inhibitors could increase the ...