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英文名称:DPP (IV) Inhibitor Screening Assay Kit 其它信息:包装信息:1mg 湖北艾普蒂生物工程有限公司 联系电话:17762444226 电子邮件:d17762444226@163.com CB指数:58 网址:www.chemicalbook.com/ShowSupplierProductsList546373/0.htm 相关信息:产品目录(2402) 用户评价 中文名称:DPP(IV)抑制剂筛选测定试剂盒 英...
DPP‐4 inhibitorGLP‐1type‐2 diabetesDiabetes has turned out to be an epidemic in the recent years all over the world, and today it has become a burden on the healthcare system. Over the years, with technological advancements, different classes of antidiabetic medications have emerged, like ...
of which DPP-4 inhibitor oral hypoglycemic drug market exceeds $20 billion. As a new type of DPP-4 inhibitor, Vildagliptin increases the level and activity of endogenous GLP-1 by blocking DPP-4-mediated GLP-1 degradation in the body. It promotes insulin secretion and inhibits glucagon secretion...
Figure 1. Nlrp1b Is Required for Dpp8/9 Inhibitor-Induced Pyroptosis (A) Structures of Val-boroPro, 1G244, and compound 8j. (B) Diagram of mouse Nlrp1b allele 1. The LF cleavage and FIIND autoproteolysis sites are indicated. (C and D) Casp1 and Nlrp1b knockout RAW 264.7 macrophage...
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International Journal of Molecular Sciences Article Finding a Potential Dipeptidyl Peptidase-4 (DPP-4) Inhibitor for Type-2 Diabetes Treatment Based on Molecular Docking, Pharmacophore Generation, and Molecular Dynamics Simulation Harika Meduru 1, Yeng-Tseng Wang 2, Jeffrey J. P. Tsai 1 and Yu-...
Table 5. Final list of phytochemicals with antagonistic potential to inhibit the four therapeutic targets of diabetes. Plants that contain at least one natural inhibitor from each protein group were also identified (Table 6) using the curated database of Indian Medicinal Plants, Phytochemistry, And...