(RIAT) initiative. The original study was a double blind, multi-center, randomized placebo-controlled trial. Women in the first 12 weeks of gestation complaining of nausea and/or vomiting were randomized to one of eight possible arms: doxylamine/pyridoxine/dicyclomine, doxylamine/pyridoxine, ...
Do not use doxylamine/pyridoxine fixed-combination therapy in nursing women.Excitement, irritability, and sedation reported in infants presumably exposed to doxylamine through human milk; infants with respiratory syndromes (e.g., apnea) may be particularly at risk.Pediatric...
Use of doxylamine succinate and pyridoxine hydrochloride delayed-release tablets is contraindicated in women who are taking monoamine oxidase inhibitors (MAOIs), which prolong and intensify the anticholinergic (drying) effects of antihistamines. Concurrent use of alcohol and other CNS depressants (such as...
The most common side effects of diphenhydramine medication include sleepiness, dizziness, blurred vision, and an upset stomach. Moreover, this medication is not recommended for children and the elderly. Although there is no evidence of any harm, this drug is not given to pregnant women or breast...
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Diclegis (doxylamine succinate and pyridoxine hydrochloride) is an antiemetic (anti-nausea and vomiting) agent used to treat nausea and vomiting in pregnant women. What Are Side Effects of Diclegis? Diclegis may cause serious side effects including: mood changes, confusion, irritability, nervousness, ...
Doxylamine is an antihistamine that was previously marketed as a treatment for nausea and vomiting in pregnant women. It was later found to have no evidence of causing birth defects and is now available as a single agent drug for sleeping medications. ...
(1997) concluded from a meta-analysis involving more than 200,000 pregnant women that use of antihistamine during early pregnancy has beneficial effects on pregnancy outcome. In addition to H1 and H2 receptor antagonists, ascorbic acid and pyridoxine, which decrease histamine levels, could also be ...