No correlation between serum concentration and degree of renal failure was found. The urinary concentrations of active doxycycline were in the same range as those of the serum. Only a small fraction of the daily dose ofdoxycyline was excreted in the urine. The present study supports earlier ...
Evaluation of Doxycycline Administration in Patients with Renal Failure and in Normal Subjects The biological half-life of doxycycline in serum was determined in 6 normal subjects and in 8 patients on maintenance haemodialysis. There was no significant difference in the half-life in the 2 groups. ...
To the Editor.— The temporally related exacerbation of renal failure associated with doxycycline use, as reported by Dr Orr and colleagues in the Archives (138:793-794, 1978), is certainly of interest and importance. However, the report serves to emphasize the caution with which one should in...
Renal Rare (0.01% to 0.1%): Increased BUN/blood urea (dose-related) Frequency not reported: Acute renal failure[Ref]Endocrine Rare (0.01% to 0.1%): Microscopic brown-black discoloration of the thyroid gland[Ref]The long-term use of tetracyclines has been associated with microscopic brown-...
Methoxyflurane The risk or severity of renal failure can be increased when Doxycycline is combined with Methoxyflurane. Methyldopa Doxycycline may decrease the excretion rate of Methyldopa which could result in a higher serum level. Methylene blue Doxycycline may decrease the excretion rate of Methylen...
In dogs and cats with renal failure, tetracyclines other than doxycycline should be avoided. Doxycycline is excreted in the intestinal tract in this situation. Tetracyclines other than doxycycline can interfere with bone growth and cause significant and permanent gray-brown or yellow discoloration of th...
Doxycycline is a semi-synthetic derivative of tetracycline family exhibiting an interesting pharmacokinetic profile since no dosage adjustment is required for renal failure. Doxycycline displays good bacteriostatic activity against most bacteria as well as anti-inflammatory activity. Bacterial resistance is main...
Nephronophthisis, the most common genetic cause of chronic renal failure in children, is a progressive tubulo-interstitial kidney disorder that is inherite... Mollet,Géraldine,Salomon,... - 《Nature Genetics》 被引量: 334发表: 2002年 A Gene Mutated in Nephronophthisis and Retinitis Pigmentosa Enc...
[110] observed in asphyxiated piglets that early administration of doxycycline during resuscitation improvedrenal perfusionand reduced markers ofrenal injury. They also found beneficial effects onhemodynamicsandmyocardial injurywith MMP-2 inactivation [111]. In rat pups, doxycycline was administered after ...
Doxycycline and Lyme Disease Treatment 27 related questions found What happens if anaplasmosis goes untreated? If left untreated,anaplasmosis can be fatal. Severe symptoms include difficulty breathing, hemorrhage, renal failure, or neurological problems. Immune-compromised individuals may develop more seve...