according to the Global Down Syndrome Foundation. The CDC estimated there were around250,700 children, teens, and adults living with Down syndrome in the U.S. in 2008. It also said 1 in every 700 babies in the U.S. are born with Down syndrome. This makes it the most commonchromosomalc...
Contrary to common expectation, the prevalence of Down syndrome (DS) is increasing. The effect of antenatal diagnosis, and the ensuing termination of many affected pregnancies, is being outweighed by the effects of childbearing later in life and the increased longevity of individuals with DS.1 ...
Adults with Down's Syndrome are at risk of developing Alzheimer's disease in later life. This paper gives an overview of the current research in the area and discusses the implications it raises for individuals, carers and service providers. Information on the link between Down's Syndrome and ...
Alzheimer's disease is typically a disease of later life, and age is the biggest known risk factor for the condition. But babies with Down syndrome, who always develop brains like those with Alzheimer's later in life, don't always go on to develop dementia. A study that I am involved i...
Objective: The hypothalamus-pituitary-thyroid (HPT) axis set point develops during the fetal period and first two years of life. We hypothesized that thyroxine treatment during these first two years, in the context of a randomized controlled trial (RCT) in children with Down syndrome, may have ...
Down syndrome is associated with increased mortality rates due to congenital cardiac defects and leukemia early in life, and with Alzheimer's disease and a tendency toward premature aging later in life. Alzheimer's disease was once considered an inexorable result of growing old with Down syndrome,...
Neurologic Phenotype in Down Syndrome As with other genetic conditions, the neurologic phenotype in DS evolves over the entire lifespan and can be quite variable between individuals. Nonetheless, there are particular DS-related neurologic conditions that are ubiquitous that clinically impact cognition and...
Down syndrome is the most common genetic cause of mental retardation.───唐氏综合症是最常见的精神迟钝的遗传病因. You might assume that a label of Down syndrome means limitation, but when he talks, you realize how rich life can be.───你可能会认为,唐氏综合症就意味着缺陷,但患者说话时你...
Premature senility in Down's syndrome Lancet. 1985 Jul 6;2(8445):34. Letter STCLAIR,D - 《Lancet》 被引量: 80发表: 1985年 Chapter 4 Alzheimer's Disease in Adults with Down Syndrome premature aging later in life. Alzheimer's disease was once considered an inexorable result of growing old...
each cell, Lejeune noted 47 in the cells of people with Down's syndrome. It was later determined that this additional chromosomal material (usually caused by triplication of the 21st chromosome) results in the physical characteristics associated with the condition and the different course in ...