In the last decades, life expectancy of persons with Down syndrome (DS) has dramatically increased and it is estimated that they will be living as long as the general population within a generation. Despite being included among the progeroid syndromes, because of the presence of features ...
The cerebral metabolic rate for glucose, as measured with positron emission tomography and fluorine-18-labeled 2-deoxy-D-glucose, was significantly higher in four healthy young subjects with trisomy 21 syndrome (Down's syndrome) than the mean rate in healthy young controls. The rate of cerebral ...
TheIndividualized Education Program(IEP) that children with Down syndrome have in public schools includes transition planning. The goal is to picture the future and think about the skills and servicesteenswill need as they become adults. When you work closely with teachers, doctors, and therapists ...
Down syndrome, congenital disorder caused by the presence in the human genome of extra genetic material from chromosome 21. The physical features of Down syndrome were first described in 1866 by British physician John Langdon Down. Learn more about the t
Down syndrome nurse practitioner perspective prevalence safety social considerations trisomy 21 This activity is designed to augment the knowledge, skills, and attitudes of nurse practitioners and assist in their ability to identify common health risks and co-occurring conditions that adults with Down Syn...
Importance Down syndrome is the most common chromosomal condition, and average life expectancy has increased substantially, from 25 years in 1983 to 60 years in 2020. Despite the unique clinical comorbidities among adults with Down syndrome, there are no clinical guidelines for the care of these pa...
Virtually all adults with Down syndrome (DS) show the neuropathological changes of Alzheimer disease (AD) by the age of 40 years. This association is partially due to overexpression of amyloid precursor protein, encoded by APP, as a result of the locatio
The increasing life expectancy of persons with Down syndrome calls for a knowledge of conditions that frequently occur in adults with the syndrome and of which health personnel should be particularly aware.The article is based on a literature search in PubMed and the authors' clinical experience wi...
Children and young adults with Down syndrome are four times more likely to be diagnosed with diabetes, according to new research led by Queen Mary University of London and King's College London. Ad The study, published inDiabetes Care, examined just under 10,000 people with Down syndrome and...
long-term follow-up data.Method This study investigated annual thyroid function tests in 200 adults with Down syndrome over a 15-year period.Results For healthy adults with Down syndrome there is a gradual increase in thyroxine and possible gradual decline in thyroid-stimulating hormone with age. ...