【答案】:用效应为纵坐标、药物浓度为横坐标作图,得直方双曲线。可将药物浓度改用对数值作图,呈典型对称S型曲线,即为量效曲线。
必应词典为您提供dose-response-curve的释义,un. 剂量反应曲线; 网络释义: 剂量-反应曲线;量效曲线;剂量反应曲线图;
A dose–response curve represents the relationship that exists in a test population (Fig. 4.7.1). There are various methods that exhibit the specific health effect under study. Values for “cumulative percentage” are represented on the “y” axis of the graph. As the dose in the “x” ax...
Dose-Response Curve Dosage, Therapeutic and Side Effects Effective, Toxic dosage and Lethal dosage Therapeutic index Potency and Variability of Drug Competitive and Non-Competitive Binding About the Author 买过这本书的人还买过 读了这本书的人还在读...
A dose-response curve was obtained at 35 keV for EBT film, and at 25, 30, and 35 keV for EBT2 and EBT3 films. Calibrations of films for 4 MV x-rays were obtained for comparison using a radiotherapy accelerator at Mary Bird Perkins Cancer Center. RESULTS: The sensitivity (NOD per ...
In non-oncology phase II dose-finding studies, the dose–response curve often plateaus in the range of interest, and there are several doses with the mean response equal to the target. In this case, it is usually of interest to find the lowest of these doses because higher doses might ...
Curve Fitting for monotonic(sigmoidal) & non-monotonic(J-shaped) concentration-response data. Prediction of mixture toxicity based on reference models such as 'concentration addition', 'independent action', and 'generalized concentration addition'. Source: https://cran.r-project.org/web/packages/mix...
Dose-response curves are key metrics in pharmacology and biology to assess phenotypic or molecular actions of bioactive compounds in a quantitative fashion. Yet, it is often unclear whether or not a measured response significantly differs from a curve wi
To determine the differences between men and women in the dose-response curve and the time-course of effect of vecuronium, we studied 60 adult patients (30 male and 30 female), ASA I, age 18-51 yr, undergoing elective plastic surgery. Anaesthesia was maintained with nitrous oxide 60% in...
The "Parameters: Nonlinear regression" dialog will now be displayed, and we'll want to find the equation/model that we want to use to generate our dose-response curve. On the "Model" tab, find expand the "Dose-response - Stimulation" group of equations, and then select the specific model...