“U-shaped” curves can be used to broadly represent a kind of dose-response connection that is curved and is seen in epidemiological and toxicological research. These curves demonstrate an apparent inversion or reversal of the effect of an otherwise dangerous drug at low or moderate dosage levels...
We hypothesized the AR would cause a shoulder on a curve of log % cell survival vs dose, while PR would cause a reduced slope or curve flattening at higher doses.Methods: Dose-response curve shapes were defined by clonogenic assays in HTB56 human lung adenocarcinoma cells (H) and its 7-...
Factors influencing the shape of the curve include changes in the blood pH, Pco2, and temperature; the presence of carbon monoxide; alterations in the constituents of the erythrocytes; and certain disease states. pulse curve sphygmogram. Spee curve (curve of Spee) the anatomic curvature of the...
Irrespective of the mode of action of the ligand of interest the ‘directionality’ of the dose response curve is irrelevant for further analysis. The TRIC response of a given target is usually a reduction in fluorescence in the detection volume upon induction of a temperature gradient, represented...
In this section, we’ll convert the Y values in data sets A and B to a common scale. This is useful when you want to compare the shape or position (EC50) of two or more curves and don’t want to be distracted by different maximum and minimum values. ...
Now, in the "Data set" dropdown menu, we'll select our second data set (not a curve) and apply a similar set of options to these symbols. This time, however, we'll use an empty square shape, and apply a light green fill and a dark green border. Finally, we'll use the "Data...
dynamic response curve 动态响应曲线 edge response curve 边缘响应曲线 pulse response curve 脉冲响应特性曲线 相似单词 dose response 【医】剂量响应 dose n. 1.(一次)剂量,一剂,一份 2.一场,一次一回 v.[T] 1.给…服药 response n. 1. 回答,答复 2. 反应,响应 3.[responses]【宗】短诗,应...
【答案】：用效应为纵坐标、药物浓度为横坐标作图，得直方双曲线。可将药物浓度改用对数值作图，呈典型对称S型曲线，即为量效曲线。
Sensitivity to a drug acting at a specific, saturable receptor typically spans a large concentration range, so dose-response curves are usually semi-logarithmic, i.e., the amount of drug is plotted as the log of drug concentration, giving them their familiar sigmoidal shape. Percent Maximal ...
range,sodose-responsecurvesareusuallysemi-logarithmic,i.e.,theamountofdrugisplottedasthelogofdrug concentration,givingthemtheirfamiliarsigmoidalshape. 0 0 25 50 75 100 Noinhibitor Inhibitor1:10 10 -9 10 -8 10 -7 10 -6 10 -5 10 -4