For sertraline there was no apparent difference between 100 , 200 and 400 mg, whereas 50 mg produced a lower response; consequently, 50 mg was designated as low and the other doses as optimal. Figure 2 displays levels of significance, ES and the mean changes in HDRS-17-sum (Figure 2a)...
Sertraline behavioral response associates closer and dose-dependently with cortical rather than hippocampal serotonergic activity in the rat forced swim stress 文档格式: .pdf 文档大小: 598.86K 文档页数: 6页 顶/踩数: 0/0 收藏人数: 0 评论次数: ...
Methods: We did a systematic review and dose-response meta-analysis of double-blind, randomised controlled trials that examined fixed doses of five selective serotonin reuptake inhibitors (SSRIs; citalopram, escitalopram, fluoxetine, paroxetine, and sertraline), venlafaxine, or mirtazapine in the acute...
Macrolide antibiotics (e.g., erythromycin), azole-antifungal agents (e.g., ketoconazole), protease inhibitors (e.g., ritonavir), fluconazole, fluvoxamine, some selective serotonin reuptake inhibitors (SSRIs) (e.g., sertraline, fluvoxamine) Inducers of CYP3A4, CYP2B6, CYP2C19, or CYP2C9 Cli...
A five dose-response curve for PFOA was tested against three fixed concentrations, 68 µM, 38 µM, and 22 µM of PFOS at 2 dpf for one day at 33 °C. These preliminary dose curves demonstrate variability with the zebrafish assay, as shown by the calculated LD50 value of 53 µ...