SP-0030: Dose calculation accuracy for lung proton therapy in clinical practicedoi:10.1016/S0167-8140(18)30340-2Followill D.Taylor P.Branco D.Kry S.Radiotherapy & Oncology
16, 2024 Select Your Interests Others Also Liked We recommend Dose Rounding of Anticancer Agents: Hematology/Oncology Pharmacy Association Position Statement By Matthew Stenger, The ASCO Post, 2018 Dose calculation of anticancer drugs: a review of the current practice and introduction of an alternative...
concentration-dependent killing agent achieves a free drug AUC/MIC ratio of 88, the logistic regression relationship allows the calculation that the probability of a good outcome is a specific number (perhaps 91%). Over the past 10 years, we have been able to generate such relationships for a...
This was a dose-escalation study, with no formal hypothesis testing, and hence no sample size calculation was performed. In view of the small numbers of study participants required for this standard 3 + 3 design study, no statistical test procedures have been performed and individual results...
[98], aiming at a weight loss, Table2. The participants’ body weight will be used for calculation of the energy requirement if the body mass index is < 30 kg/m2. If the BMI is > 30 kg/m2, the body weight in the equation will be adjusted to corresponding to a BMI =...
43 Fourth, the sample size calculation was powered to detect a reduction of 1 infection per season assuming 1 infection per month, but the data demonstrated that children experienced on average 1 laboratory-confirmed upper respiratory tract infection per season. Preliminary calculations using a Poisson...
Analysis We will compare the proportion with microbial cure at 4 weeks between arms using the Chi square test, and 95% confidence intervals for the difference between Table 2 Sample size calculation Doxycycline cure 98% cure 96% cure Power 80% 90% 80% Difference to detecta % 538 720 762 ...
These tools are developed to perform nodule detection in combination with nodule volumetry and growth rate calculation, in theory without the interference and initiation of the radiologist [26, 41]. Future studies need to determine whether this fully automated workflow of the software algorithms has ...
Dose calculation Dose to medium, Dose to water To maximize the power of clinical trials, and to ensure results are broadly interpretable, it is essential that dose be calculated consistently across all participating institutions [1]. Clinical practice must also be consistent with the framework of ...
where PA is permeability area (PA = effective contact area × permeability),CPis concentration in peritoneal cavity, andCBis concentration in the blood. Although the equation permits calculation of the pharmacokinetic advantage, the model does not tell anything about the specific penetration of the can...