Serum B12 activity has been controlled frequently after one and/or two series of five i.m. injections of 1 mg hydroxocobalamin (OHB12) on alternate days followed by injection of 1 mg OHB12 every three months for up to four years. Results from 23 patients with B12 deficiency indicated that...
For replenishing stores of vitamin B12, 1000 μg should be given by intramuscular injection three times per week for two weeks. This can then be done weekly for four weeks, then once monthly. In cases where absorption is not an issue, the maintenance dose can also be given orally.[2] Su...
Your doctor may have you take extravitamin B12while you are taking metformin. Take only the amount of vitamin B12 that your doctor has prescribed. What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. ...
METABOLIC: Magnesium levels, especially in patients taking other drugs that could result in hypomagnesemia or those on long-term therapy; Vitamin B12 levels, especially in patients on long-term therapy MUSCULOSKELETAL: Bone fractures, especially in patients at high-risk for osteoporosis-related events ...
hydroxocobalamin application could be an alternative for intramuscular injection.Six patients with plasma cobalamin concentrations of < 200 ng/L were recruited... WB Slot,FW Merkus,SV Deventer,... - 《Gastroenterology》 被引量: 427发表: 1997年 Normalization of plasma vitamin B12 concentration by int...
Secondly, the method was applicated to the determination of vitamin B12 in pharmaceutical injection and in serum. Recoveries ranged from 98,5 to 100,9 % for drugs. Comparison with results obtained with the microparticule enzymatic method (MEIA Abbott) for serums were less satisfactory....
vitamin B12with activity equivalent to theendogenousform of vitamin B12. The chemical name is α-(5,6-dimethylbenzimidazolyl) cyanocobamide. The cobalt content is 4.35%. The molecular formula is C63H88CoN14O14P, which corresponds to a molecular weight of 1355.4 and the following structural ...
Fusilev is not indicated forpernicious anemiaand megaloblasticanemiasecondary to the lack ofvitamin B12, because of the risk of progression of neurologic manifestations despite hematologicremission. Dosage for Fusilev Important Use Information Fusilev is indicated for intravenous administration only. Do not...
31. Herbert, V. and Jacob, E. Destruction of vitamin B12 by ascorbic acid. JAMA, 230:241-242, 1974. 32. Belfield, W.O. and Stone, I. Megascorbic prophylaxis and megascorbic therapy: A new orthomolecular modality in veterinary medicine. Journal of the International Academy of Preventive Me...
naturally occurring mineral that is important for the normal functioning of many systems in the body, including nerve function, electrical conduction in the heart, protein synthesis, bone formation andblood pressureregulation. Magnesium sulfate (antidote) is administered as an intravenous injection or in...