The meaning of DOPAMINERGIC is liberating, activated by, or involving dopamine or related substances. How to use dopaminergic in a sentence.
Origin of dopaminergic1 First recorded in 1970–75; dopamine + -ergic Discover More Example Sentences They injected the virus directly into the midbrain of the Parkinson’s mouse model, where the team had depleted most dopaminergic neurons with the chemical, oxidopamine. From NautilusAdvertisement...
Dopamine releasing (DA) neurons within the midbrain are important for a variety of brain functions and behavioural processes like voluntary movement control, learning, cognition, and motivation1,2,3,4. The cell bodies of DA midbrain neurons are predominantly located in two overlapping nuclei, the ...
Poor graft survival limits the use of primary dopaminergic neurons for neural repair in Parkinson’s disease. Injectable hydrogels have the potential to significantly improve the outcome of such reparative approaches by providing a physical matrix for ce
Auditory forms of social learning have been particularly well-studied in songbirds58,59,60,61,62, where dopaminergic signaling is involved in both song learning and song production63. Indeed, Tanaka et al.64showed that exposure to a live, singing tutor selectively activated dopamine neurons in a...
Animal studies show that midbrain dopamine neurons are activated by unexpected salient events. In psychotic patients, neurochemical studies have confirmed subcortical striatal dysregulation of dopaminergic neurotransmission, whereas functional magnetic resonance imaging (fMRI) studies of salience tasks have ...
By contrast, threatening visual stimuli inactivate some of these neurons, resulting in dis-inhibition of visuomotor transformation and initiation of escape behavior. The distinct patterns of dopaminergic-inhibitory neural module's visual responses account for this stimulus-specific visuomotor transformation ...
The first model is that recurrent stimulant use results in adaptive changes in the dopamine system that lead to reduced firing of dopamine neurons, potentially similar to the depolarization blockade that is seen after a period of successive firing,93 with consequently reduced dopamine synthesis and ...
4. Activation of D2 receptors on substantia nigra dopamine neurons with 365 nm light. Blue arrow indicates point of 1 ms flash. In blue is the response with CyHQ-O-DA (150 μM), in red is the response after the addition of cocaine (3 μM) to inhibit dopamine transport, and in bla...
Exposure to novelty prevents the reduction of TH + terminals after the administration of Aβ1‑42 oligomers in the hippocampus Several studies have found that DA neurons are susceptible to the toxic effects of Aβ1-42, and their axonal processes are diminished in ...